A quad-copter is a simple form of UAV with four rotors. It can be either autonomous or controlled remotely by a human on the ground. In the recent past, it has been extensively used in various fields like military, surveillance, medical, etc. The current research related to quad-copters focuses on providing an efficient design for the different components used to build them. In the present work, a quad-copter frame structure is designed with an optimized mass of the frame, using the generative design technique. The resulting mass-optimized frame structure is numerically simulated for the varying magnitudes of transverse loads at different frame locations. The maximum stress developed and deformation resulting from the application of transverse loads on the frame is numerically studied. It is found that the frame designed using PA6 material weighs 11.7% lesser as compared to the frame earlier considered by Singh et al. . Also, the deformation is found to be minimum when a maximum load of 35N is applied to the frame.