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Proceedings Papers

Effects of Media Stirring and Presence of Nutrient Channels on Functional Properties of Large Engineered Cartilage Constructs

Alexander D. Cigan, Robert J. Nims, Michael B. Albro, Clark T. Hung, Gerard A. Ateshian

Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT39A001, June 26–29, 2013

Paper No: SBC2013-14128

DOI: https://doi.org/10.1115/SBC2013-14128

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Topics: Cartilage, Osteoarthritis, Tissue engineering, Young's modulus

Proceedings Papers

Prolonged Treatment of Ultra-Low Dose Chondroitinase ABC Improves Matrix Production in Engineered Cartilage

Grace D. O’Connell, Victoria Cui, Robert J. Nims, Adam B. Nover, Gerard A. Ateshian, Clark T. Hung

Paper No: SBC2013-14191

DOI: https://doi.org/10.1115/SBC2013-14191

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Topics: Cartilage, Stress, Bearings, Biological tissues, Equilibrium (Physics), Soft tissues

Proceedings Papers

Combined Effects of Scaffold Material and Mechanical Stimulation on the Formation of Tissue Engineered Constructs Using Tendon and Ligament Progenitor Cells

Andrew P. Breidenbach, Nathaniel A. Dyment, Yinhui Lu, Jason T. Shearn, David W. Rowe, Karl E. Kadler, David L. Butler

Paper No: SBC2013-14379

DOI: https://doi.org/10.1115/SBC2013-14379

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Topics: Biological tissues, Stem cells, Tendons, Wounds, Maintenance, Mechanical properties, Musculoskeletal system, Thermoelectric coolers, Tissue engineering

Proceedings Papers

Viscoelastic Properties of a Synthetic Meniscus Implant

M. Shemesh, R. Asher, E. Zylberberg, F. Guilak, E. Linder-Ganz, J. J. Elsner

Paper No: SBC2013-14406

DOI: https://doi.org/10.1115/SBC2013-14406

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Topics: Viscoelasticity, Biomechanics, Compression, Creep, Durability, Dynamic testing (Engineering), Dynamic testing (Materials), Finite element analysis, Knee, Osteoarthritis

Proceedings Papers

Nano-Scale and Micro-Scale Substrate Architectures Direct Collagen Alignment in Tendon Neo-Tissue Formation

Christopher L. Gilchrist, David S. Ruch, Dianne Little, Farshid Guilak

Paper No: SBC2013-14474

DOI: https://doi.org/10.1115/SBC2013-14474

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Topics: Architecture, Biological tissues, Microscale devices, Nanoscale phenomena, Tendons, Biomaterials, Tissue engineering

Proceedings Papers

Functional Consequences of Glucose and Oxygen Deprivation in Engineered MSC-Based Cartilage Constructs

Megan J. Farrell, John Shin, Robert L. Mauck

Paper No: SBC2013-14495

DOI: https://doi.org/10.1115/SBC2013-14495

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Topics: Cartilage, Glucose, Oxygen, Chondrocytes, Biological tissues, Mechanical properties, Maintenance, Stem cells

Proceedings Papers

Towards Engineering Whole Bones via Endochondral Ossification

Eamon J. Sheehy, Tatiana Vinardell, Conor T. Buckley, Daniel J. Kelly

Paper No: SBC2013-14504

DOI: https://doi.org/10.1115/SBC2013-14504

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Topics: Bone, Hydrogels, Tissue engineering, Biological tissues, Cartilage, Oxygen, Stem cells

Proceedings Papers

Chondroitinase-ABC Digestion and Dynamic Loading Increase Tension-Compression Nonlinearity in Tissue-Engineered Cartilage

Terri-Ann N. Kelly, Brendan L. Roach, Charles R. Mackenzie-Smith, Adam B. Nover, Eben G. Estell, Grace D. O’Connell, Gerard A. Ateshian, Clark T. Hung

Paper No: SBC2013-14621

DOI: https://doi.org/10.1115/SBC2013-14621

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Topics: Biological tissues, Cartilage, Compression, Dynamic testing (Materials), Tension, Mechanical properties, Strength (Materials), Tensile strength, Young's modulus

Proceedings Papers

Using a Biphasic Finite Element Model of the Human Knee Joint to Identify Robust Designs for a Meniscal Substitute

Erin R. Leatherman, Hongqiang Guo, Suzanne A. Maher, Thomas J. Santner

Paper No: SBC2013-14629

DOI: https://doi.org/10.1115/SBC2013-14629

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Topics: Finite element model, Knee, Disks, Mechanical properties, Orthopedics, Shapes, Surgery, Wedges

Proceedings Papers

Mechanical and Electrical Stimulation Induces Calcium-Sensitive Mechanical Properties of Myoblast Derived Engineered Fibers

Andrew K. Mason, Ryan A. Koppes, Douglas M. Swank, David T. Corr

Paper No: SBC2013-14646

DOI: https://doi.org/10.1115/SBC2013-14646

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Topics: Biological tissues, Biomedicine, Dynamic response, Fibers, Mechanical properties, Muscle, Physiology, Tissue engineering, Wounds

Proceedings Papers

Inclusion of a Collagen-GAG Sponge Core Improves Tangent Modulus of Multi-Phase PEGDM Hydrogel Constructs

Kirsten R. C. Kinneberg, Andra Nelson, Rachel C. Paietta, Justine J. Roberts, Brendan A. Harley, Stephanie J. Bryant, Virginia L. Ferguson

Paper No: SBC2013-14711

DOI: https://doi.org/10.1115/SBC2013-14711

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Topics: Cartilage, Hydrogels, Maintenance, Osteoarthritis, Surgery, Tissue engineering

Proceedings Papers

Engineering Meniscus Form and Function via Multi-Layer Cell-Seeded Nanofibrous Scaffolds With Circumferentially Aligned Fibers

Matthew B. Fisher, Nicole Söegaard, John L. Esterhai, Robert L. Mauck

Paper No: SBC2013-14741

DOI: https://doi.org/10.1115/SBC2013-14741

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Topics: Fibers, Biological tissues, Anisotropy, Electrospinning, Knee, Mechanical properties, Orthopedics, Osteoarthritis, Rotation, Stem cells

Proceedings Papers

Mechanical Stimulation Provides the Key Induction Signal for Tenogenic Differentiation of Human Mesenchymal Stem Cells in Braided Nanofibrous Scaffolds

Andrew M. Handorf, John G. Barber, Tyler J. Allee, Ray Vanderby, Wan-Ju Li

Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 391-392, June 22–25, 2011

Paper No: SBC2011-53130

DOI: https://doi.org/10.1115/SBC2011-53130

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Topics: Economics , Electromagnetic induction, Health systems, Orthopedics, Signals, Stem cells, Tendons, Wounds

Proceedings Papers

Dynamic Culture Improves Mechanical Functionality of MSC-Laden Tissue Engineered Constructs in a Depth-Dependent Manner

Megan J. Farrell, Eric S. Comeau, Robert L. Mauck

Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 393-394, June 22–25, 2011

Paper No: SBC2011-53442

DOI: https://doi.org/10.1115/SBC2011-53442

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Topics: Biological tissues, Cartilage, Chondrocytes, Equilibrium (Physics), Hydrogels, Mechanical properties, Stem cells, Tissue engineering

Proceedings Papers

Muscle Injury Attenuates BMP-2 Mediated Tissue Regeneration in a Novel Rat Model of Composite Bone and Muscle Injury

Nick J. Willett, M. Alice Li, Brent A. Uhrig, Gordon L. Warren, Robert E. Guldberg

Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 395-396, June 22–25, 2011

Paper No: SBC2011-53589

DOI: https://doi.org/10.1115/SBC2011-53589

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Topics: Biological tissues, Bone, Composite materials, Muscle, Wounds, Soft tissues, Musculoskeletal system, Biomechanics, Diseases, Maintenance

Proceedings Papers

Characterization of αGal(−) ECM Bioscaffolds: An Indication for Application in Tissue Engineering

Rui Liang, Matthew B. Fisher, Guoguang Yang, Christine Hall, Savio L-Y. Woo

Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 397-398, June 22–25, 2011

Paper No: SBC2011-53601

DOI: https://doi.org/10.1115/SBC2011-53601

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Topics: Biomechanics, Tendons, Tissue engineering, Urinary bladder

Proceedings Papers

The Effect of Cyclic Hydrostatic Pressure on the Functional Development of Cartilaginous Tissues Engineered Using Bone Marrow Derived Mesenchymal Stem Cells

Eric G. Meyer, Conor T. Buckley, Daniel J. Kelly

Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 399-400, June 22–25, 2011

Paper No: SBC2011-53634

DOI: https://doi.org/10.1115/SBC2011-53634

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Topics: Biological tissues, Bone, Hydrostatic pressure, Stem cells, Cartilage, Chondrocytes, Mechanical properties, Maintenance, Orthopedics, Tissue engineering

Proceedings Papers

Effects of Passaging on the Migration Response of Synovium-Derived Stem Cells to an Applied DC Electric Field

Andrea R. Tan, Elena Alegre-Aguarón, Divya N. Dujari, Sonal R. Sampat, J. Chloë Bulinski, Gerard A. Ateshian, Clark T. Hung

Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 401-402, June 22–25, 2011

Paper No: SBC2011-53674

DOI: https://doi.org/10.1115/SBC2011-53674

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Topics: Electric fields, Stem cells, Chondrocytes, Cartilage, Biological tissues, Bone, Maintenance, Membranes, Poles (Building), Tissue engineering

Proceedings Papers

A Simple, Cost-Effective Method to Improve Cell Viability in Microniche Culture Systems

Lindsay F. Mignone, Shirley Masand, Jeffrey D. Zahn, David I. Shreiber

Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 379-380, June 16–19, 2010

Paper No: SBC2010-19189

DOI: https://doi.org/10.1115/SBC2010-19189

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Topics: Assaying, Biological tissues, Bonding, Bubbles, Experimental methods, Glass, Hydrogels, Membranes, Microfluidics, Microscale devices

Proceedings Papers

Co-Culture of a Chondrocyte Monolayer With Engineered Cartilage Constructs Immediately Increases Tissue Properties

Andrea R. Tan, Elizabeth Y. Dong, Byunghwi Rho, Sonal R. Sampat, J. Chloe Bulinski, Gerard A. Ateshian, Clark T. Hung

Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 381-382, June 16–19, 2010

Paper No: SBC2010-19459

DOI: https://doi.org/10.1115/SBC2010-19459

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Topics: Biological tissues, Cartilage, Chondrocytes, Agar, Maintenance, Stem cells, Tissue engineering, Young's modulus

NARROW

Effects of Media Stirring and Presence of Nutrient Channels on Functional Properties of Large Engineered Cartilage Constructs

Prolonged Treatment of Ultra-Low Dose Chondroitinase ABC Improves Matrix Production in Engineered Cartilage

Combined Effects of Scaffold Material and Mechanical Stimulation on the Formation of Tissue Engineered Constructs Using Tendon and Ligament Progenitor Cells

Viscoelastic Properties of a Synthetic Meniscus Implant

Nano-Scale and Micro-Scale Substrate Architectures Direct Collagen Alignment in Tendon Neo-Tissue Formation

Functional Consequences of Glucose and Oxygen Deprivation in Engineered MSC-Based Cartilage Constructs

Towards Engineering Whole Bones via Endochondral Ossification

Chondroitinase-ABC Digestion and Dynamic Loading Increase Tension-Compression Nonlinearity in Tissue-Engineered Cartilage

Using a Biphasic Finite Element Model of the Human Knee Joint to Identify Robust Designs for a Meniscal Substitute

Mechanical and Electrical Stimulation Induces Calcium-Sensitive Mechanical Properties of Myoblast Derived Engineered Fibers

Inclusion of a Collagen-GAG Sponge Core Improves Tangent Modulus of Multi-Phase PEGDM Hydrogel Constructs

Engineering Meniscus Form and Function via Multi-Layer Cell-Seeded Nanofibrous Scaffolds With Circumferentially Aligned Fibers

Mechanical Stimulation Provides the Key Induction Signal for Tenogenic Differentiation of Human Mesenchymal Stem Cells in Braided Nanofibrous Scaffolds

Dynamic Culture Improves Mechanical Functionality of MSC-Laden Tissue Engineered Constructs in a Depth-Dependent Manner

Muscle Injury Attenuates BMP-2 Mediated Tissue Regeneration in a Novel Rat Model of Composite Bone and Muscle Injury

Characterization of αGal(−) ECM Bioscaffolds: An Indication for Application in Tissue Engineering

The Effect of Cyclic Hydrostatic Pressure on the Functional Development of Cartilaginous Tissues Engineered Using Bone Marrow Derived Mesenchymal Stem Cells

Effects of Passaging on the Migration Response of Synovium-Derived Stem Cells to an Applied DC Electric Field

A Simple, Cost-Effective Method to Improve Cell Viability in Microniche Culture Systems

Co-Culture of a Chondrocyte Monolayer With Engineered Cartilage Constructs Immediately Increases Tissue Properties

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