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Proceedings Papers

Strain-Dependent TGF Beta-1 Synthesis and Activation by Aortic Valve Interstitial Cells

W. David Merryman, Michael P. Nilo, Joanne E. Murphy-Ullrich
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 137-138, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192874
https://doi.org/10.1115/SBC2008-192874
View Paper titled, Strain-Dependent TGF Beta-1 Synthesis and Activation by Aortic Valve Interstitial Cells
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Topics: Valves, Aorta, Fibroblasts, Stress
Proceedings Papers

Non-Planar Shape of the Mitral Annulus Reduces Systolic Strain on the Posterior Leaflet by Increasing Leaflet Curvature

Muralidhar Padala, Michael S. Sacks, Ajit P. Yoganathan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 139-140, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192996
https://doi.org/10.1115/SBC2008-192996
View Paper titled, Non-Planar Shape of the Mitral Annulus Reduces Systolic Strain on the Posterior Leaflet by Increasing Leaflet Curvature
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Topics: Annulus, Shapes, Valves, Cardiac cycle, Surgery
Proceedings Papers

Extracellular Matrix-Contractile Response Coupling of the Aortic Heart Valve Interstitial Cell

David E. Schmidt, W. David Merryman, Michael S. Sacks
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 141-142, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193171
https://doi.org/10.1115/SBC2008-193171
View Paper titled, Extracellular Matrix-Contractile Response Coupling of the Aortic Heart Valve Interstitial Cell
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Topics: Valves, Stiffness, Biological tissues, Mechanical properties, Bending (Stress), Computational methods, Engineering simulation, Finite element model, Probes, Simulation
Proceedings Papers

Development of an Implantable Heart Valve Force Transducer

Morten O. Jensen, Peter Johansen, Hans Nygaard
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 247-248, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192309
https://doi.org/10.1115/SBC2008-192309
View Paper titled, Development of an Implantable Heart Valve Force Transducer
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Topics: Transducers, Valves, Maintenance, Heart valve prostheses, Myocardium, Physiology, Strain gages, Stress
Proceedings Papers

Comparison of Right Ventricular Stroke Work for Tetralogy Patient and Normal Subject

Ashish Das, William Gottliebson, Rupak K. Banerjee
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 845-846, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193145
https://doi.org/10.1115/SBC2008-193145
View Paper titled, Comparison of Right Ventricular Stroke Work for Tetralogy Patient and Normal Subject
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Topics: Aorta, Damage, Diseases, Maintenance, Valves
Proceedings Papers

A Fluid-Structure Interaction Model for 3D Heart Valve Dynamics

Sarah C. Vigmostad, H. S. Udaykumar, Jia Lu, Michael S. Sacks, K. B. Chandran
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1101-1102, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193116
https://doi.org/10.1115/SBC2008-193116
View Paper titled, A Fluid-Structure Interaction Model for 3D Heart Valve Dynamics
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Topics: Dynamics (Mechanics), Fluid structure interaction, Valves, Failure, Heart valve prostheses, Biological tissues, Hemodynamics, Stress, Structural failures, Tension
Proceedings Papers

Imaging of Aortic Valve Collagen Structure and Internal Deformations Using a Novel Digital Image Correlation Technique

Todd C. Doehring, Michael Kahelin
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 699-700, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193202
https://doi.org/10.1115/SBC2008-193202
View Paper titled, Imaging of Aortic Valve Collagen Structure and Internal Deformations Using a Novel Digital Image Correlation Technique
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Topics: Deformation, Imaging, Valves, Biological tissues, Computer software, Computers, Fibers, Filters, Membranes, Optics
Proceedings Papers

Determining the Mechanical Properties of Coronary Sinus for Percutaneous Mitral Valve Repair

Thuy M. Pham, Xuan H. Nguyen, Milton DeHerrera, Wei Sun
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 709-710, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193226
https://doi.org/10.1115/SBC2008-193226
View Paper titled, Determining the Mechanical Properties of Coronary Sinus for Percutaneous Mitral Valve Repair
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Topics: Maintenance, Mechanical properties, Valves, Blood, Leakage, Pressing, Surgery
Proceedings Papers

Reduction of Flow-Induced Blood Damage in Bileaflet Mechanical Heart Valves Through Passive Flow Control

David W. Murphy, Lakshmi P. Dasi, Ari Glezer, Ajit P. Yoganathan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 549-550, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192980
https://doi.org/10.1115/SBC2008-192980
View Paper titled, Reduction of Flow-Induced Blood Damage in Bileaflet Mechanical Heart Valves Through Passive Flow Control
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Topics: Blood, Damage, Flow (Dynamics), Flow control, Heart valve prostheses, Valves, Shear stress, Platelets, Vortices, Generators
Proceedings Papers

A Combined Theoretical-Experimental Paradigm for Studying Mechanical Conditioning of Tissue Engineered Arteries

Julia Raykin, Alexander Rachev, Michael Zaucha, Rudolph L. Gleason, Jr.
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 75-76, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192746
https://doi.org/10.1115/SBC2008-192746
View Paper titled, A Combined Theoretical-Experimental Paradigm for Studying Mechanical Conditioning of Tissue Engineered Arteries
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Topics: Biological tissues, Bending (Stress), Biomechanics, Blood vessels, Shear stress, Stress, Biochemistry, Biology, Engineering disciplines, Materials science
Proceedings Papers

Multiscale Structural Analysis of Porcine Aortic Heart Valves Using a Collagen Fiber Network (CFN) Micromodel

Hee Sun Kim, Choon Hwai Yap, Lakshmi Prasad Dasi, Ajit P. Yoganathan, Rami Haj-Ali
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 451-452, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192800
https://doi.org/10.1115/SBC2008-192800
View Paper titled, Multiscale Structural Analysis of Porcine Aortic Heart Valves Using a Collagen Fiber Network (CFN) Micromodel
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Topics: Fibers, Structural analysis, Valves, Mechanical behavior, Anisotropy, Biological tissues, Deformation, Engineering simulation, Kinematics, Simulation
Proceedings Papers

In Vivo Evaluation of Composite Polymeric Materials for Potential Application in a Trileaflet Heart Valve

Qiang Wang, Siobhain L. Gallocher, Amit Datye, Leonard Pinchuk, Richard T. Schoephoerster
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 757-758, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192889
https://doi.org/10.1115/SBC2008-192889
View Paper titled, In Vivo Evaluation of Composite Polymeric Materials for Potential Application in a Trileaflet Heart Valve
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Topics: Polymer composites, Valves, Biocompatibility, Design, Polymers, Textiles, Composite materials, Durability, Hemodynamics
Proceedings Papers

The Intrinsic Durability of Aortic Valve ECM in Absence of Cellular Maintenance

Jun Liao, Erinn M. Joyce, Hugh L. Jones, Mina Tahai, Ali Borazjani, W. David Merryman, Michael S. Sacks
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 659-660, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193110
https://doi.org/10.1115/SBC2008-193110
View Paper titled, The Intrinsic Durability of Aortic Valve ECM in Absence of Cellular Maintenance
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Topics: Durability, Maintenance, Valves, Biological tissues, Design, Surgery
Proceedings Papers

Controlled Cyclic Stretching of Tissue Engineered Heart Valves: Effects on Mechanical Properties and ECM Organization

Zeeshan H. Syedain, Robert T. Tranquillo
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 363-364, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192583
https://doi.org/10.1115/SBC2008-192583
View Paper titled, Controlled Cyclic Stretching of Tissue Engineered Heart Valves: Effects on Mechanical Properties and ECM Organization
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Topics: Biological tissues, Mechanical properties, Valves, Bioreactors, Fibroblasts, Maintenance, Performance, Tissue engineering
Proceedings Papers

Fluid Structure Interaction Analysis of Blood Flow Through a Mechanical Heart Valve

Alejandro Roldán, Nancy Sweitzer, Tim Osswald, Naomi Chesler
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 365-366, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192585
https://doi.org/10.1115/SBC2008-192585
View Paper titled, Fluid Structure Interaction Analysis of Blood Flow Through a Mechanical Heart Valve
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Topics: Blood flow, Fluid structure interaction, Heart valve prostheses, Valves, Blood, Finite element methods, Flow (Dynamics), Modeling, Pulsatile flow
Proceedings Papers

Mechanical Properties of the Fetal Bovine Bladder Lamina Propria and Their Correlation With Changes in Extracellular Matrix

Robert S. Cargill, II, Kevin K. Toosi, Edward J. Macarak
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 671-672, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193131
https://doi.org/10.1115/SBC2008-193131
View Paper titled, Mechanical Properties of the Fetal Bovine Bladder Lamina Propria and Their Correlation With Changes in Extracellular Matrix
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Topics: Damage, Kidney, Mechanical properties, Pressure, Spinal cord, Storage, Urinary bladder, Valves, Wounds
Proceedings Papers

Comparison of In Vitro and In Vivo Testing of Fluid Diodes as a Pulmonary Heart Valve Replacement

Tiffany Camp, Richard Figliola, Tim McQuinn, T.-Y. Hsia, Tim Conover
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 677-678, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193156
https://doi.org/10.1115/SBC2008-193156
View Paper titled, Comparison of In Vitro and In Vivo Testing of Fluid Diodes as a Pulmonary Heart Valve Replacement
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Topics: Fluids, Testing, Valves, Pressure gradient, Cardiovascular system, Flow (Dynamics)
Proceedings Papers

Effect of Leaflet Anisotropy, Coaptation Curvature, and Stent Flexibility on the Stress Concentrations and In Vitro Function of Polymer Trileaflet Heart Valves

Siobhain L. Gallocher, Amit Datye, Kuang-Hsi Wu, Leonard Pinchuk, Richard T. Schoephoerster
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 487-488, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192860
https://doi.org/10.1115/SBC2008-192860
View Paper titled, Effect of Leaflet Anisotropy, Coaptation Curvature, and Stent Flexibility on the Stress Concentrations and In Vitro Function of Polymer Trileaflet Heart Valves
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Topics: Anisotropy, Polymers, Stents, Stress, Valves, Design, Durability, Engineering prototypes, Fatigue, Fibers
Proceedings Papers

Correlating Leaflet Design and Closing Dynamics With Turbulent Flows Near Bileaflet Mechanical Heart Valves

Luke H. Herbertson, Steven Deutsch, Keefe B. Manning
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1091-1092, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192508
https://doi.org/10.1115/SBC2008-192508
View Paper titled, Correlating Leaflet Design and Closing Dynamics With Turbulent Flows Near Bileaflet Mechanical Heart Valves
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Topics: Design, Dynamics (Mechanics), Heart valve prostheses, Turbulence, Valves, Fluid mechanics, Patient treatment, Thrombosis
Proceedings Papers

Simulations of the Hinge Flow Fields of a Bileaflet Mechanical Heart Valve Under Physiologic Pulsatile Aortic Conditions

Hélène A. Simon, Liang Ge, Iman Borazjani, Fotis Sotiropoulos, Ajit P. Yoganathan
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1093-1094, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192939
https://doi.org/10.1115/SBC2008-192939
View Paper titled, Simulations of the Hinge Flow Fields of a Bileaflet Mechanical Heart Valve Under Physiologic Pulsatile Aortic Conditions
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Topics: Engineering simulation, Flow (Dynamics), Heart valve prostheses, Hinges, Physiology, Simulation, Valves, Design, Blood, Hemodynamics