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Proceedings Papers

Cytokine Convection Affects Cancer Metastasis by a Shear Rate Dependent Mechanism

Meghan H. Hoskins, Shile Liang, Payal Khanna, Robert F. Kunz, Cheng Dong
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 513-514, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192904
https://doi.org/10.1115/SBC2008-192904
View Paper titled, Cytokine Convection Affects Cancer Metastasis by a Shear Rate Dependent Mechanism
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Topics: Cancer, Convection, Shear rate, Skin
Proceedings Papers

A Comprehensive Flow Study of the 12 cc Penn State Pulsatile Pediatric Ventricular Assist Device

Breigh N. Roszelle, Steven Deutsch, Keefe B. Manning
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1037-1038, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192743
https://doi.org/10.1115/SBC2008-192743
View Paper titled, A Comprehensive Flow Study of the 12 cc Penn State Pulsatile Pediatric Ventricular Assist Device
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Topics: Flow (Dynamics), Pediatrics, Ventricular assist devices, Blood, Biomedicine, Design, Flow visualization, Fluid dynamics, Gates (Closures), Lung
Proceedings Papers

A Novel Scanning Method to Measure Shear Rate Around a Thrombus Using Micro Particle Image Velocimetry

Elham Tolouei, Warwick Nesbitt, Andreas Fouras, Josie Carberry, Shaun Jackson
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 881-882, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192706
https://doi.org/10.1115/SBC2008-192706
View Paper titled, A Novel Scanning Method to Measure Shear Rate Around a Thrombus Using Micro Particle Image Velocimetry
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Topics: Microparticles, Shear rate, Thrombosis, Diseases, Platelets, Wounds
Proceedings Papers

A Fluid Dynamics Study Focusing on Wall Shear Rates Within the Penn State 12 cc Pulsatile Pediatric Ventricular Assist Device: A Comparison of Mechanical Heart Valve Types

Benjamin T. Cooper, Breigh N. Roszelle, Tobias C. Long, Steven Deutsch, Keefe B. Manning
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 679-680, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-175441
https://doi.org/10.1115/SBC2007-175441
View Paper titled, A Fluid Dynamics Study Focusing on Wall Shear Rates Within the Penn State 12 cc Pulsatile Pediatric Ventricular Assist Device: A Comparison of Mechanical Heart Valve Types
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Topics: Fluid dynamics, Heart valve prostheses, Pediatrics, Shear rate, Ventricular assist devices, Valves, Flow (Dynamics), Disks, Jets, Particulate matter
Proceedings Papers

Pediatric Blood Viscoelasticity Measurements

Neema Nair, George M. Pantalos, M. Keith Sharp
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 515-516, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176463
https://doi.org/10.1115/SBC2007-176463
View Paper titled, Pediatric Blood Viscoelasticity Measurements
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Topics: Hemorheology, Pediatrics, Erythrocytes, Deformation, Flow (Dynamics), Shear (Mechanics), Shear rate, Cardiovascular devices, Viscoelasticity
Proceedings Papers

Time Resolved DPIV Analysis of Pulsatile Flow in Symmetric Stenotic Arteries: A Comparison Between Arterial and Coronary Flow

Satyaprakash Babu Karri, Etebari Ali, Pavlos Vlachos
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 519-520, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176533
https://doi.org/10.1115/SBC2007-176533
View Paper titled, Time Resolved DPIV Analysis of Pulsatile Flow in Symmetric Stenotic Arteries: A Comparison Between Arterial and Coronary Flow
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Topics: Flow (Dynamics), Pulsatile flow, Shear stress, Blood flow, Flow separation, Hemodynamics, Platelets, Shear (Mechanics), Shear rate
Proceedings Papers

CFD Model of Dynamic Thrombus Growth With and Without Shear Rate Dependant Deposition

David L. Bark, Jr., David N. Ku
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 529-530, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176667
https://doi.org/10.1115/SBC2007-176667
View Paper titled, CFD Model of Dynamic Thrombus Growth With and Without Shear Rate Dependant Deposition
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Topics: Computational fluid dynamics, Shear rate, Thrombosis, Platelets, Risk, Accidents, Adhesion, Atherosclerosis, Blood, Fluid mechanics
Proceedings Papers

Tissue Engineered Tumor Microvessels to Study the Role of Flow Shear Stress on Endothelial Barrier Function

Cara F. Buchanan, Elizabeth Voigt, Pavlos P. Vlachos, Marissa Nichole Rylander
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT45A005, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14592
https://doi.org/10.1115/SBC2013-14592
View Paper titled, Tissue Engineered Tumor Microvessels to Study the Role of Flow Shear Stress on Endothelial Barrier Function
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Topics: Biological tissues, Flow (Dynamics), Shear stress, Tumors, Blood, Stress, Vessels, Blood vessels, Cancer, Drainage
Proceedings Papers

Effects of Channel Size and Shear Rate on Platelet Margination

Marmar Mehrabadi, Cyrus K. Aidun, David N. Ku
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT05A012, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14599
https://doi.org/10.1115/SBC2013-14599
View Paper titled, Effects of Channel Size and Shear Rate on Platelet Margination
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Topics: Atherosclerosis, Blood, Platelets, Risk, Shear rate, Thrombosis
Proceedings Papers

Platelet Retraction Forces Induced Under High Shear Gradient Activation

Lucas H. Ting, Shirin Feghhi, Nathan J. Sniadecki
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT49A003, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14211
https://doi.org/10.1115/SBC2013-14211
View Paper titled, Platelet Retraction Forces Induced Under High Shear Gradient Activation
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Topics: Platelets, Shear (Mechanics), Vessels, Blood vessels, Hemodynamics, Shear rate, Stents, Valves
Proceedings Papers

Experimental Investigation of Blood Cells Flowing Through Microscale Geometries Using MicroPIV

Vishwanath Somashekar, Michael G. Olsen, K. B. Chandran, H. S. Udaykumar
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 255-256, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80575
https://doi.org/10.1115/SBC2012-80575
View Paper titled, Experimental Investigation of Blood Cells Flowing Through Microscale Geometries Using MicroPIV
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Topics: Blood, Microscale devices, Platelets, Thrombosis, Erythrocytes, Flow (Dynamics), Microchannels, Reynolds number, Shear (Mechanics), Blood flow
Proceedings Papers

Shear Rate Characteristics of Growing Thrombus on a Stenosis in a Coronary Sized Vessel

David L. Bark, Jr., Andrea N. Para, David N. Ku
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1141-1142, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206766
https://doi.org/10.1115/SBC2009-206766
View Paper titled, Shear Rate Characteristics of Growing Thrombus on a Stenosis in a Coronary Sized Vessel
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Topics: Shear rate, Thrombosis, Vessels, Flow (Dynamics), Platelets, Shear (Mechanics), Atherosclerosis, Blood vessels
Proceedings Papers

Computer Simulations of the Blood Flows and the Growth of Stenosis in Arteries With Bends and Bifurcations

Biyue Liu, Dalin Tang
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 421-422, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-203654
https://doi.org/10.1115/SBC2009-203654
View Paper titled, Computer Simulations of the Blood Flows and the Growth of Stenosis in Arteries With Bends and Bifurcations
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Topics: Bifurcation, Blood flow, Computer simulation, Atherosclerosis, Shear stress, Blood, Brain, Myocardium, Aorta, Biological tissues
Proceedings Papers

Effect of Blood Viscosity on Thrombosis Potential Near a Step Wall Transition

Scott C. Corbett, Amin Ajdari, Ahmet U. Coskun, Hamid N.-Hashemi
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 457-458, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206629
https://doi.org/10.1115/SBC2009-206629
View Paper titled, Effect of Blood Viscosity on Thrombosis Potential Near a Step Wall Transition
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Topics: Hemorheology, Thrombosis, Blood, Shear rate, Platelets, Stress, Artificial organs, Blood flow, Damage, Geometry
Proceedings Papers

A 3-D Computational Model of L-Selectin-PSGL-1 Dependent Homotypic Leukocyte Binding and Rupture in Shear Flow

Vijay K. Gupta, Charles D. Eggleton
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 671-672, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80862
https://doi.org/10.1115/SBC2012-80862
View Paper titled, A 3-D Computational Model of L-Selectin-PSGL-1 Dependent Homotypic Leukocyte Binding and Rupture in Shear Flow
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Topics: Leukocytes, Rupture, Shear flow, Adhesion, Shear rate, Equilibrium (Physics), Fluid-dynamic forces, Diseases, Thrombosis, Adhesives
Proceedings Papers

Visualization and Measurement of Flow-Induced Dynamic Motion of Red Blood Cells Using Tracking Confocal Micro-PIV System

Marie Oshima, Masamichi Oishi, Haruyuki Kinoshita, Teruo Fujii
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 341-342, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80516
https://doi.org/10.1115/SBC2012-80516
View Paper titled, Visualization and Measurement of Flow-Induced Dynamic Motion of Red Blood Cells Using Tracking Confocal Micro-PIV System
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Topics: Erythrocytes, Flow (Dynamics), Visualization, Blood vessels, Membranes, Non-Newtonian flow, Shapes, Shear rate
Proceedings Papers

Mechanisms of Platelet Capture Under Very High Shear

P. J. Wellings, D. N. Ku
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 955-956, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53786
https://doi.org/10.1115/SBC2011-53786
View Paper titled, Mechanisms of Platelet Capture Under Very High Shear
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Topics: Platelets, Shear (Mechanics), Thrombosis, Blood, Shear rate, Biophysics, Bonding, Hemodynamics, Micromechanics (Engineering)
Proceedings Papers

Comprehensive Simulations of the Microcirculation in Rat Spinotrapezius Muscle Fascia

Frank G. Jacobitz, Adam M. Jones
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 737-738, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53291
https://doi.org/10.1115/SBC2011-53291
View Paper titled, Comprehensive Simulations of the Microcirculation in Rat Spinotrapezius Muscle Fascia
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Topics: Engineering simulation, Muscle, Simulation, Vessels, Blood, Elasticity, Diseases, Microscopes, Rheology, Shear rate
Proceedings Papers

Creating a Low Volume Model of Occlusive Thrombosis

Andrea N. Para, David Ku
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1113-1114, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53624
https://doi.org/10.1115/SBC2011-53624
View Paper titled, Creating a Low Volume Model of Occlusive Thrombosis
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Topics: Thrombosis, Shear (Mechanics), Platelets, Diseases, Gravity (Force), Rupture, Shear rate
Proceedings Papers

Experimental Wall Shear Estimation as a Means of Predicting Thrombus Formation Within a 50cc Penn State Blood Pump

Jason C. Nanna, Stephen R. Topper, Ning Yang, Breigh N. Roszelle, Steven Deutsch, Keefe B. Manning
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 127-128, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19552
https://doi.org/10.1115/SBC2010-19552
View Paper titled, Experimental Wall Shear Estimation as a Means of Predicting Thrombus Formation Within a 50cc Penn State Blood Pump
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Topics: Blood, Pumps, Shear (Mechanics), Thrombosis, Flow (Dynamics), Fluid mechanics, Patient treatment, Shear rate, Ventricular assist devices