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Proceedings Papers

Parametric Finite Element Analysis of Physical Stimuli Resulting From Mechanical Stimulation of Tissue Engineered Cartilage

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Omotunde M. Babalola, Lawrence J. Bonassar
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 91-92, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192633
https://doi.org/10.1115/SBC2008-192633
View Paper titled, Parametric Finite Element Analysis of Physical Stimuli Resulting From Mechanical Stimulation of Tissue Engineered Cartilage
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Topics: Biological tissues, Cartilage, Finite element analysis, Maintenance, Chondrocytes, Density, Osteoblasts, Patient treatment, Stem cells, Tissue engineering
Proceedings Papers

Sub-Micron 3D Fluorescent Imaging and Visualization of Remodeling Cavities in Cancellous Bone

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Craig R. Slyfield, Ryan E. Tomlinson, Evgeniy V. Tkachenko, Kyle E. Neimeyer, Grant J. Steyer, David L. Wilson, Christopher J. Hernandez
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 21-22, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193099
https://doi.org/10.1115/SBC2008-193099
View Paper titled, Sub-Micron 3D Fluorescent Imaging and Visualization of Remodeling Cavities in Cancellous Bone
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Topics: Bone, Cavities, Imaging, Visualization, Mechanical properties, Stress, Biological tissues, Finite element analysis, Materials properties, Microscale devices
Proceedings Papers

The Effects of the Inhibition of Connexin 43 on Pre-Osteoblasts and Their Response to Mechanical Stimulation

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Danese M. Joiner, Ethan L. H. Daley, Steven A. Goldstein
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 409-410, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192700
https://doi.org/10.1115/SBC2008-192700
View Paper titled, The Effects of the Inhibition of Connexin 43 on Pre-Osteoblasts and Their Response to Mechanical Stimulation
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Topics: Osteoblasts, Bone, Fluids, Junctions, Shear stress, Gravity (Force), Stress
Proceedings Papers

Micromotions at the Bone Implant Interface Up-Regulate Osteoblasts-Mediated Activation of Osteoclasts in Ex Vivo Human Samples

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Vincent A. Stadelmann, Dominique P. Pioletti
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 865-866, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-175743
https://doi.org/10.1115/SBC2007-175743
View Paper titled, Micromotions at the Bone Implant Interface Up-Regulate Osteoblasts-Mediated Activation of Osteoclasts in Ex Vivo Human Samples
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Topics: Bone, Osteoblasts, Biological tissues, Arthroplasty, Prostheses, Risk
Proceedings Papers

Tissue Strain Transduction and Amplification at the Osteocyte as a Result of Microstructural Changes in the Bone Matrix

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Amber Rath Bonivtch, Lynda F. Bonewald, Daniel P. Nicolella
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 893-894, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176139
https://doi.org/10.1115/SBC2007-176139
View Paper titled, Tissue Strain Transduction and Amplification at the Osteocyte as a Result of Microstructural Changes in the Bone Matrix
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Topics: Biological tissues, Bone, Deformation, Flow (Dynamics), Fluids, Hydrostatic pressure, Osteoblasts, Shear stress, Strain gages
Proceedings Papers

Investigation of Osteoclast Resorption Mechanisms in a Hybrid Cellular Automaton Model of Bone Remodeling

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Charles L. Penninger, Ryan K. Roeder, Glen L. Niebur, John E. Renaud
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 351-352, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176171
https://doi.org/10.1115/SBC2007-176171
View Paper titled, Investigation of Osteoclast Resorption Mechanisms in a Hybrid Cellular Automaton Model of Bone Remodeling
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Topics: Bone, Robots, Biological tissues, Damage, Maintenance, Minerals, Osteoblasts, Stress
Proceedings Papers

Microvascular Oreintation During Angiogenesis: Effects of Mechanical Stretch and Boundary Conditions

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Laxminarayanan Krishnan, Clayton J. Underwood, Steve A. Maas, Benjamin Ellis, Tejas C. Kode, James B. Hoying, Jeffrey A. Weiss
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1033-1034, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176598
https://doi.org/10.1115/SBC2007-176598
View Paper titled, Microvascular Oreintation During Angiogenesis: Effects of Mechanical Stretch and Boundary Conditions
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Topics: Boundary-value problems, Endothelial cells, Chondrocytes, Cordage, Fibers, Fibroblasts, Muscle, Osteoblasts, Vessels
Proceedings Papers

Analysis of the Active Response of Cells to Cyclic Loading Using a Modified AFM System

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P. Weafer, N. Reynolds, W. Ronan, E. Dowling, S. Jarvis, P. McGarry
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT35A005, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14793
https://doi.org/10.1115/SBC2013-14793
View Paper titled, Analysis of the Active Response of Cells to Cyclic Loading Using a Modified AFM System
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Topics: Atomic force microscopy, Deformation, Biological tissues, Maintenance, Osteoblasts, Tension, Testing
Proceedings Papers

Primary Cilia Knockdown Reduces the Number of Stromal Cells in Three Dimensional Ex Vivo Culture

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Thomas R. Coughlin, Matthew Haugh, Muriel Voisin, Evelyn Birmingham, Laoise M. McNamara, Glen L. Niebur
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT50A006, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14723
https://doi.org/10.1115/SBC2013-14723
View Paper titled, Primary Cilia Knockdown Reduces the Number of Stromal Cells in Three Dimensional Ex Vivo Culture
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Topics: Bone, Osteoblasts, Signals, Stem cells
Proceedings Papers

Murine Osteochondral Stem Cells Express Collagen Type I More Strongly on PDMS Substrates Than on Tissue Culture Plastic

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William S. Van Dyke, Ozan Akkus, Eric Nauman
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT17A008, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14272
https://doi.org/10.1115/SBC2013-14272
View Paper titled, Murine Osteochondral Stem Cells Express Collagen Type I More Strongly on PDMS Substrates Than on Tissue Culture Plastic
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Topics: Biological tissues, Plasma desorption mass spectrometry, Stem cells, Stiffness, Osteoblasts, Bone, Anchorage, Chondrocytes, Fibers, Stress
Proceedings Papers

Fluid-Structure Interaction Modelling Predicts That Strain Transfer Through Focal Attachments of Osteoblast Cells are the Primary Mediators of Mechanical Stimulation Under Fluid Flow

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T. J. Vaughan, M. G. Haugh, L. M. McNamara
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT09A012, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14259
https://doi.org/10.1115/SBC2013-14259
View Paper titled, Fluid-Structure Interaction Modelling Predicts That Strain Transfer Through Focal Attachments of Osteoblast Cells are the Primary Mediators of Mechanical Stimulation Under Fluid Flow
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Topics: Fluid dynamics, Fluid structure interaction, Modeling, Osteoblasts, Bone, Flow (Dynamics), Fluids, Physiology
Proceedings Papers

Mechanotransductive Effects of Acoustic Radiation Force on Osteoblastic Primary Cilium, Cytoskeleton and Ca 2+ Influx

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Y. X. Qin, S. Zhang, J. Cheng
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 39-40, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80582
https://doi.org/10.1115/SBC2012-80582
View Paper titled, Mechanotransductive Effects of Acoustic Radiation Force on Osteoblastic Primary Cilium, Cytoskeleton and Ca 2+ Influx
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Topics: Acoustics, Radiation (Physics), Ultrasound, Bone, Signals, Biological tissues, Bone fractures, Osteoblasts, Temperature, Transients (Dynamics)
Proceedings Papers

Osteocytes in Bone Can Regulate the Turnover of Adjacent Mineralized Growth Plate Cartilage

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Lieke G. E. Cox, Corrinus C. van Donkelaar, Bert van Rietbergen, Rik Huiskes, Keita Ito
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 53-54, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206251
https://doi.org/10.1115/SBC2009-206251
View Paper titled, Osteocytes in Bone Can Regulate the Turnover of Adjacent Mineralized Growth Plate Cartilage
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Topics: Bone, Cartilage, Osteoblasts, Junctions, Linings (Textiles)
Proceedings Papers

Calcium Signaling in Bone Cell Networks Induced by Fluid Flow

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X. Lucas Lu, Bo Huo, Andrew D. Baik, X. Edward Guo
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 291-292, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206043
https://doi.org/10.1115/SBC2009-206043
View Paper titled, Calcium Signaling in Bone Cell Networks Induced by Fluid Flow
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Topics: Bone, Fluid dynamics, Osteoblasts, Junctions, Oscillations, Printing, Self-assembly
Proceedings Papers

Alteration of Bone’s Nonlinear Elastic and Viscoelastic Nanomechanical Properties Is Triggered by Low Intensity Pulsed Ultrasound

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Suzanne Ferreri, Yi-Xian Qin
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 45-46, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206711
https://doi.org/10.1115/SBC2009-206711
View Paper titled, Alteration of Bone’s Nonlinear Elastic and Viscoelastic Nanomechanical Properties Is Triggered by Low Intensity Pulsed Ultrasound
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Topics: Ultrasound, Signals, Bone, Biological tissues, Fracture (Materials), Fracture (Process), Nanoscale phenomena, Strength (Materials), Viscoelasticity, Materials properties
Proceedings Papers

Bone Marrow Adipogenesis Is Affected by Insulin-Like Growth Factor-1 Complexes

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J. Christopher Fritton, Yuki Kawashima, Hui Sun, Yingjie Wu, Wilson Mejia, Hayden W. Courtland, Clifford J. Rosen, Shoshana Yakar
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 569-570, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206158
https://doi.org/10.1115/SBC2009-206158
View Paper titled, Bone Marrow Adipogenesis Is Affected by Insulin-Like Growth Factor-1 Complexes
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Topics: Bone, Biological tissues, Maintenance, Osteoblasts, Stem cells
Proceedings Papers

Biopolymer Polyelectrolyte Complex Nanocomposites for Bone Tissue Engineering

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Devendra Verma, Kalpana Katti, Dinesh Katti
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1185-1186, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206390
https://doi.org/10.1115/SBC2009-206390
View Paper titled, Biopolymer Polyelectrolyte Complex Nanocomposites for Bone Tissue Engineering
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Topics: Biopolymers, Bone, Nanocomposites, Adhesion, Porosity, Biocompatibility, Biodegradation, Biological tissues, Fibers, Osteoblasts
Proceedings Papers

A Semi-3D Real-Time Imaging Technique for Measuring Bone Cell Deformation Under Fluid Flow

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Andrew D. Baik, X. Lucas Lu, Bo Huo, X. Sherry Liu, Cheng Dong, X. Edward Guo
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 823-824, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206524
https://doi.org/10.1115/SBC2009-206524
View Paper titled, A Semi-3D Real-Time Imaging Technique for Measuring Bone Cell Deformation Under Fluid Flow
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Topics: Bone, Deformation, Fluid dynamics, Imaging, Adhesion, Flow (Dynamics), Fluids, Microscopy, Osteoblasts, Shear (Mechanics)
Proceedings Papers

Thermal Effects on Osteogenesis of Human Mesenchymal Stem Cells

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Jing Chen, Sihong Wang
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 309-310, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80885
https://doi.org/10.1115/SBC2012-80885
View Paper titled, Thermal Effects on Osteogenesis of Human Mesenchymal Stem Cells
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Topics: Stem cells, Temperature effects, Heat, Osteoblasts, Bone, Hydrogels, Maintenance, Osteoarthritis, Patient treatment, Self-assembly
Proceedings Papers

Aortic Valve Interstitial Cell Activation Does Not Occur at Low Tissue Stiffness During Embryogenesis

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Young Wook Chun, Joey Barnett, W. David Merryman
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1041-1042, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80501
https://doi.org/10.1115/SBC2012-80501
View Paper titled, Aortic Valve Interstitial Cell Activation Does Not Occur at Low Tissue Stiffness During Embryogenesis
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Topics: Biological tissues, Stiffness, Valves, Diseases, Vickers hardness testing, Artificial limbs, Design, Enzymes, Maintenance, Osteoblasts