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Proceedings Papers

Design of Experiments for Exposure of Astrocytes to Elevated Hydrostatic Pressure and Hypoxia

Shadi Rajabi, Craig A. Simmons, C. Ross Ethier
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1017-1018, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192558
https://doi.org/10.1115/SBC2008-192558
View Paper titled, Design of Experiments for Exposure of Astrocytes to Elevated Hydrostatic Pressure and Hypoxia
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Topics: Damage, Experimental design, Hydrostatic pressure, Pressure
Proceedings Papers

Effect of Traction Load on the Biomechanical Behavior of Cervical, Thoracic, and Lumbar Spinal Segments: A Finite Element Analysis

Mozammil Hussain, Rodger Tepe
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 719-720, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193246
https://doi.org/10.1115/SBC2008-193246
View Paper titled, Effect of Traction Load on the Biomechanical Behavior of Cervical, Thoracic, and Lumbar Spinal Segments: A Finite Element Analysis
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Topics: Biomechanics, Finite element analysis, Stress, Traction, Disks, Patient treatment, Physiology, Anatomy, Annulus, Compression
Proceedings Papers

Synergistic and Additive Effects of Hydrostatic Pressure and Growth Factor Application on Engineered Articular Cartilage Constructs

Benjamin D. Elder, Kyriacos A. Athanasiou
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 823-824, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192104
https://doi.org/10.1115/SBC2008-192104
View Paper titled, Synergistic and Additive Effects of Hydrostatic Pressure and Growth Factor Application on Engineered Articular Cartilage Constructs
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Topics: Cartilage, Hydrostatic pressure, Biomechanics, Self-assembly
Proceedings Papers

Effects of Hydrostatic Pressure on Meniscus Cell-Seeded PLLA Scaffolds

Najmuddin J. Gunja, Kyriacos A. Athanasiou
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1019-1020, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176496
https://doi.org/10.1115/SBC2007-176496
View Paper titled, Effects of Hydrostatic Pressure on Meniscus Cell-Seeded PLLA Scaffolds
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Topics: Hydrostatic pressure, Cartilage, Chondrocytes, Deformation, Tissue engineering
Proceedings Papers

Dynamic Hydrostatic Pressurization Differentially Regulates Extracellular Matrix Elaboration by Bovine Inner and Outer Annulus Fibrosus Cells Seeded on 3-D Polymer Scaffolds

Anna T. Reza, Steven B. Nicoll
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1029-1030, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176539
https://doi.org/10.1115/SBC2007-176539
View Paper titled, Dynamic Hydrostatic Pressurization Differentially Regulates Extracellular Matrix Elaboration by Bovine Inner and Outer Annulus Fibrosus Cells Seeded on 3-D Polymer Scaffolds
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Topics: Annulus, Hydrostatics, Polymers, Biological tissues, Hydrostatic pressure, Intervertebral discs, Mechanical admittance, Surgery, Tissue engineering
Proceedings Papers

Mesenchymal Progenitor Cells Differentially Respond to Mechanical Stimulation: Morphology, Proliferation, Gene and Protein Expression

Timothy M. Maul, Douglas W. Chew, Alejandro Nieponice, David A. Vorp
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 797-798, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-175994
https://doi.org/10.1115/SBC2007-175994
View Paper titled, Mesenchymal Progenitor Cells Differentially Respond to Mechanical Stimulation: Morphology, Proliferation, Gene and Protein Expression
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Topics: Proteins, Stem cells, Cardiovascular system, Hydrostatic pressure, Muscle, Shear stress
Proceedings Papers

Tissue Strain Transduction and Amplification at the Osteocyte as a Result of Microstructural Changes in the Bone Matrix

Amber Rath Bonivtch, Lynda F. Bonewald, Daniel P. Nicolella
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 893-894, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176139
https://doi.org/10.1115/SBC2007-176139
View Paper titled, Tissue Strain Transduction and Amplification at the Osteocyte as a Result of Microstructural Changes in the Bone Matrix
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Topics: Biological tissues, Bone, Deformation, Flow (Dynamics), Fluids, Hydrostatic pressure, Osteoblasts, Shear stress, Strain gages
Proceedings Papers

Calcium Signaling is a Key Regulator of Mesenchymal Stem Cell Response to Hydrostatic Pressure

A. J. Steward, D. J. Kelly, D. R. Wagner
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT17A014, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14347
https://doi.org/10.1115/SBC2013-14347
View Paper titled, Calcium Signaling is a Key Regulator of Mesenchymal Stem Cell Response to Hydrostatic Pressure
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Topics: Hydrostatic pressure, Stem cells, Stress, Biological tissues, Bearings, Cartilage, Deformation, Fluctuations (Physics), Fluids, Ionic mobility
Proceedings Papers

Pressure Gradients in the Trabecular Pore Space of Femurs During Physiologic Loading

Thomas A. Metzger, Stephen A. Schwaner, Glen L. Niebur
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT09A017, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14433
https://doi.org/10.1115/SBC2013-14433
View Paper titled, Pressure Gradients in the Trabecular Pore Space of Femurs During Physiologic Loading
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Topics: Biological tissues, Bone, Fluid dynamics, Hydrostatic pressure, Physiology, Pressure, Pressure gradient, Proteins
Proceedings Papers

Articular Cartilage and Meniscal Fibrocartilage Mechanics: Evidence for Differences in Ultrastructure and Function of Proteoglycans

An M. Nguyen, Marc E. Levenston
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 927-928, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204457
https://doi.org/10.1115/SBC2009-204457
View Paper titled, Articular Cartilage and Meniscal Fibrocartilage Mechanics: Evidence for Differences in Ultrastructure and Function of Proteoglycans
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Topics: Cartilage, Biological tissues, Stress, Fibers, Fluids, Hydrostatic pressure, Permeability, Shear (Mechanics)
Proceedings Papers

Validation of a Finite Element Model of Passive Force and Pressure in Skeletal Muscle

Duane A. Morrow, Tammy L. Haut Donahue, Gregory M. Odegard, Kenton R. Kaufman
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 339-340, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206211
https://doi.org/10.1115/SBC2009-206211
View Paper titled, Validation of a Finite Element Model of Passive Force and Pressure in Skeletal Muscle
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Topics: Finite element model, Muscle, Pressure, Finite element analysis, Biological tissues, Constitutive equations, Deformation, Elongation, Hydrostatic pressure, Microsensors
Proceedings Papers

An Analytical Solution for Flexible Substrates Undergoing Small Equibiaxial Strains

Martin Y. M. Chiang, Joy Dunkers
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 701-702, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206285
https://doi.org/10.1115/SBC2009-206285
View Paper titled, An Analytical Solution for Flexible Substrates Undergoing Small Equibiaxial Strains
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Topics: Compression, Fluids, Hydrostatic pressure, Pressure, Shear (Mechanics), Shear stress, Signals, Tension
Proceedings Papers

Comparison of Mechanosensitivity of Human Primary-Cultured Osteoblast Cells and Human Osteosarcoma Cell Line Under Hydrostatic Pressure

Yasaman Ganji, Mehran Kasra
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 825-826, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80030
https://doi.org/10.1115/SBC2012-80030
View Paper titled, Comparison of Mechanosensitivity of Human Primary-Cultured Osteoblast Cells and Human Osteosarcoma Cell Line Under Hydrostatic Pressure
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Topics: Hydrostatic pressure, Osteoblasts, Bone, Pressure, Primary cells, Patient treatment
Proceedings Papers

Oscillatory Fluid Flow Affects the Osteogenic Differentiation of Human Bone Marrow Stromal Cells in a Primary Cilium Dependent Manner

David A. Hoey, Christopher R. Jacobs
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 331-332, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53435
https://doi.org/10.1115/SBC2011-53435
View Paper titled, Oscillatory Fluid Flow Affects the Osteogenic Differentiation of Human Bone Marrow Stromal Cells in a Primary Cilium Dependent Manner
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Topics: Bone, Fluid dynamics, Cavities, Diseases, Hydrostatic pressure, Osteoblasts, Osteoporosis, Shear stress
Proceedings Papers

Mechanically Induced Calcium Release From Bone Matrix Triggers Intracellular Ca 2+ Signalling in Osteoblasts: A Novel Mechanotransduction Mechanism

Xuanhao Sun, Vipuil Kishore, Kateri Fites, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 333-334, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53446
https://doi.org/10.1115/SBC2011-53446
View Paper titled, Mechanically Induced Calcium Release From Bone Matrix Triggers Intracellular Ca 2+ Signalling in Osteoblasts: A Novel Mechanotransduction Mechanism
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Topics: Bone, Osteoblasts, Damage, Maintenance, Signals, Deformation, Fluid dynamics, Hydrostatic pressure, Microcracks, Shear (Mechanics)
Proceedings Papers

A Novel Mechanical Bioreactor System Allowing Simultaneous Strain and Fluid Shear Stress on Cell Monolayers

W. Scott Van Dyke, Eric Nauman, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1241-1242, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53595
https://doi.org/10.1115/SBC2011-53595
View Paper titled, A Novel Mechanical Bioreactor System Allowing Simultaneous Strain and Fluid Shear Stress on Cell Monolayers
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Topics: Bioreactors, Fluids, Shear stress, Bone, Fluid dynamics, Signals, Biology, Constitutive equations, Hydrostatic pressure, Osteoblasts
Proceedings Papers

Calcium Efflux From Bone Matrix in Response to Mechanical Loading

Xuanhao Sun, Eric S. McLamore, D. Marshall Porterfield, Ozan Akkus
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 505-506, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53625
https://doi.org/10.1115/SBC2011-53625
View Paper titled, Calcium Efflux From Bone Matrix in Response to Mechanical Loading
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Topics: Bone, Deformation, Fluids, Hydrostatic pressure, Maintenance, Shear (Mechanics)
Proceedings Papers

An Optical Approach for Studying the Cellular Mechanotransduction of Hydrostatic Pressure by Bladder Urothelial Cells

Shawn Olsen, Jiro Nagatomi
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1245-1246, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53872
https://doi.org/10.1115/SBC2011-53872
View Paper titled, An Optical Approach for Studying the Cellular Mechanotransduction of Hydrostatic Pressure by Bladder Urothelial Cells
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Topics: Hydrostatic pressure, Membranes, Deformation, Imaging, Sodium, Transients (Dynamics)
Proceedings Papers

The Effect of Cyclic Hydrostatic Pressure on the Functional Development of Cartilaginous Tissues Engineered Using Bone Marrow Derived Mesenchymal Stem Cells

Eric G. Meyer, Conor T. Buckley, Daniel J. Kelly
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 399-400, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53634
https://doi.org/10.1115/SBC2011-53634
View Paper titled, The Effect of Cyclic Hydrostatic Pressure on the Functional Development of Cartilaginous Tissues Engineered Using Bone Marrow Derived Mesenchymal Stem Cells
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Topics: Biological tissues, Bone, Hydrostatic pressure, Stem cells, Cartilage, Chondrocytes, Mechanical properties, Maintenance, Orthopedics, Tissue engineering
Proceedings Papers

Electrophysiological Investigation of Hydrostatic Pressure Mechanotransduction by Urothelial Cell Lines

Kevin D. Champaigne, Sarette N. Jenderny, Jiro Nagatomi
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1239-1240, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53518
https://doi.org/10.1115/SBC2011-53518
View Paper titled, Electrophysiological Investigation of Hydrostatic Pressure Mechanotransduction by Urothelial Cell Lines
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Topics: Hydrostatic pressure, Pressure, Cell membranes, Linings (Textiles), Membranes, Ruthenium, Signals, Tension, Transients (Dynamics), Urinary bladder