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Proceedings Papers

A CFD Computational Model for the Optimization of Transport Phenomena in a Rotating Hollow Fiber Bioreactor for Artificial Liver

Filippo Consolo, Marco Caronna, Franco M. Montevecchi, Gianfranco B. Fiore, Alberto Redaelli
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 477-478, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192844
https://doi.org/10.1115/SBC2008-192844
View Paper titled, A CFD Computational Model for the Optimization of Transport Phenomena in a Rotating Hollow Fiber Bioreactor for Artificial Liver
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Topics: Bioreactors, Computational fluid dynamics, Fibers, Liver, Optimization, Transport phenomena, Failure
Proceedings Papers

Metabolite Transport Inside Channeled Porous Scaffolds for Haematopoietic Stem Cell Culture: A Computational Study

Marco Cantini, Gianfranco B. Fiore, Alberto Redaelli, Monica Soncini
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 481-482, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192852
https://doi.org/10.1115/SBC2008-192852
View Paper titled, Metabolite Transport Inside Channeled Porous Scaffolds for Haematopoietic Stem Cell Culture: A Computational Study
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Topics: Biomedicine, Bioreactors, Computational fluid dynamics, Design, Flow (Dynamics), Fluid dynamics, Stem cells, Tissue engineering
Proceedings Papers

Non-Destructive and Non-Invasive Assessment of Mechanical Properties in Heart Valve Tissue Engineering

Jeroen Kortsmit, Niels J. B. Driessen, Marcel C. M. Rutten, Frank P. T. Baaijens
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 135-136, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192799
https://doi.org/10.1115/SBC2008-192799
View Paper titled, Non-Destructive and Non-Invasive Assessment of Mechanical Properties in Heart Valve Tissue Engineering
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Topics: Mechanical properties, Tissue engineering, Valves, Biological tissues, Bioreactors, Deformation, Mechanical behavior, Strength (Materials)
Proceedings Papers

Controlled Cyclic Stretching of Tissue Engineered Heart Valves: Effects on Mechanical Properties and ECM Organization

Zeeshan H. Syedain, Robert T. Tranquillo
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 363-364, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192583
https://doi.org/10.1115/SBC2008-192583
View Paper titled, Controlled Cyclic Stretching of Tissue Engineered Heart Valves: Effects on Mechanical Properties and ECM Organization
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Topics: Biological tissues, Mechanical properties, Valves, Bioreactors, Fibroblasts, Maintenance, Performance, Tissue engineering
Proceedings Papers

A Novel Bioreactor Engineered With Mass Transport and Storage as Key Design Specifications

Mei Niu, Gengbei Shi, Robin N. Coger
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 899-900, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192610
https://doi.org/10.1115/SBC2008-192610
View Paper titled, A Novel Bioreactor Engineered With Mass Transport and Storage as Key Design Specifications
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Topics: Bioreactors, Design, Liver, Storage
Proceedings Papers

Non Invasive Assessment of Leaflet Deformation in Heart Valve Tissue Engineering

Jeroen Kortsmit, Niels J. B. Driessen, Marcel C. M. Rutten, Frank P. T. Baaijens
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 143-144, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-175643
https://doi.org/10.1115/SBC2007-175643
View Paper titled, Non Invasive Assessment of Leaflet Deformation in Heart Valve Tissue Engineering
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Topics: Deformation, Tissue engineering, Valves, Biological tissues, Mechanical properties, Pressure, Bioreactors, Design, Strength (Materials), Stress
Proceedings Papers

Sliding Contact Modulates ECM Expression in Chondroctye-Laden Agarose Gels

Alice H. Huang, Robert L. Mauck
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1011-1012, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176427
https://doi.org/10.1115/SBC2007-176427
View Paper titled, Sliding Contact Modulates ECM Expression in Chondroctye-Laden Agarose Gels
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Topics: Agar, Anisotropy, Bearings, Biological tissues, Bioreactors, Cartilage, Chondrocytes, Diseases, Friction, Hydrogels
Proceedings Papers

Local Non-Affine Deformations and Fiber Kinematics of Elastomeric Electrospun Scaffolds

Todd D. Courtney, Jun Liao, William R. Wagner, Michael S. Sacks
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1045-1046, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176720
https://doi.org/10.1115/SBC2007-176720
View Paper titled, Local Non-Affine Deformations and Fiber Kinematics of Elastomeric Electrospun Scaffolds
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Topics: Deformation, Fibers, Kinematics, Biological tissues, Bioreactors, Ester, Mechanical properties, Modeling, Stiffness, Stress
Proceedings Papers

Microfluidics Bioreactor: A Platform for Studying Capillary Morphogenesis in Response to Biochemical and Biophysical Cues

Vernella V. Vickerman Kelley, Roger D. Kamm
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 57-58, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176655
https://doi.org/10.1115/SBC2007-176655
View Paper titled, Microfluidics Bioreactor: A Platform for Studying Capillary Morphogenesis in Response to Biochemical and Biophysical Cues
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Topics: Bioreactors, Chemical properties, Endothelial cells, Flow (Dynamics), Microfluidics, Physiology, Self-assembly, Shear (Mechanics), Shear stress, Stress
Proceedings Papers

Novel Tissue-Engineered Heart Valve

Zeeshan Syedain, Lee Meier, Jay Reimer, Robert Tranquillo
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT15A006, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14783
https://doi.org/10.1115/SBC2013-14783
View Paper titled, Novel Tissue-Engineered Heart Valve
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Topics: Biological tissues, Valves, Bioreactors, Design, Fibroblasts, Flow (Dynamics), Patient treatment, Pediatrics
Proceedings Papers

A Novel Multi-Stimuli Bioreactor for Tissue Engineering Cartilage

Carlos A. Carmona-Moran, Timothy M. Wick
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT17A023, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14586
https://doi.org/10.1115/SBC2013-14586
View Paper titled, A Novel Multi-Stimuli Bioreactor for Tissue Engineering Cartilage
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Topics: Bioreactors, Cartilage, Tissue engineering, Biological tissues, Manufacturing systems, Osteoarthritis, Shear stress
Proceedings Papers

A Novel Perfusion Bioreactor for 3D Cell Culture in Microgravity Conditions

Giuseppe Isu, Diana Massai, Giulia Cerino, Diego Gallo, Cristina Bignardi, Alberto Audenino, Umberto Morbiducci
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT22A004, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14502
https://doi.org/10.1115/SBC2013-14502
View Paper titled, A Novel Perfusion Bioreactor for 3D Cell Culture in Microgravity Conditions
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Topics: Bioreactors, Reduced gravity environments, Biological tissues, Biomedicine, Cultured cells, Damage, Maintenance, Mass transfer, Physiology, Rotation
Proceedings Papers

Development of a Traumatic Brain Injury Bioreactor

Zachery E. Heller, Joseph Wyatt, Jeffery C. Wolchok
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT55A014, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14316
https://doi.org/10.1115/SBC2013-14316
View Paper titled, Development of a Traumatic Brain Injury Bioreactor
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Topics: Bioreactors, Traumatic brain injury, Wounds, Brain, Testing
Proceedings Papers

Assembly and Characterization of 3D, Vascularized Breast Cancer Tissue Mimics

Lauren Marshall, Andra Frost, Tim Fee, Joel Berry
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT62A004, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14199
https://doi.org/10.1115/SBC2013-14199
View Paper titled, Assembly and Characterization of 3D, Vascularized Breast Cancer Tissue Mimics
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Topics: Biological tissues, Cancer, Manufacturing, Drugs, Physiology, Anticancer drugs, Bioreactors, Blood flow, Diffusion (Physics), Fibroblasts
Proceedings Papers

Four Week Durability of Combined RF Ablation and Cryo-Anchoring Treatment for Mitral Valve Prolapse

Steven M. Boronyak, W. David Merryman
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT30A002, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14198
https://doi.org/10.1115/SBC2013-14198
View Paper titled, Four Week Durability of Combined RF Ablation and Cryo-Anchoring Treatment for Mitral Valve Prolapse
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Topics: Durability, Radiofrequency ablation, Valves, Biological tissues, Stiffness, Ablation (Vaporization technology), Bioreactors, Catheters, Maintenance, Mechanical testing
Proceedings Papers

A Novel Bioreactor for In Vitro Electro-Mechanical Stimulation of Cardiac Constructs

Andrea Pavesi, Riccardo Vismara, Stefano Lorenzoni, Franco M. Montevecchi, Gianfranco B. Fiore
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1119-1120, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206650
https://doi.org/10.1115/SBC2009-206650
View Paper titled, A Novel Bioreactor for In Vitro Electro-Mechanical Stimulation of Cardiac Constructs
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Topics: Biological tissues, Biomaterials, Bioreactors, Cardiovascular system, Diseases, Maintenance, Tissue engineering
Proceedings Papers

A Novel Bioreactor for Continuous Monitoring of Force-Displacement

Richard A. Lasher, Monir K. Parikh, Robert W. Hitchcock
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1003-1004, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-205775
https://doi.org/10.1115/SBC2009-205775
View Paper titled, A Novel Bioreactor for Continuous Monitoring of Force-Displacement
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Topics: Bioreactors, Displacement, Biological tissues, Mechanical properties
Proceedings Papers

Cytoskeletal Control of Mesenchymal Stem Cell Nuclear Deformation on Nanofibrous Scaffolds

Ashwin S. Nathan, Brendon M. Baker, Robert L. Mauck
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 773-774, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206855
https://doi.org/10.1115/SBC2009-206855
View Paper titled, Cytoskeletal Control of Mesenchymal Stem Cell Nuclear Deformation on Nanofibrous Scaffolds
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Topics: Deformation, Stem cells, Biological tissues, Bioreactors, Signals, Tensile deformation, Adhesion, Mechanical properties, Shapes, Tissue engineering
Proceedings Papers

Transmural Flow Bioreactor for Vascular Tissue Engineering

Jason W. Bjork, Robert T. Tranquillo
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1281-1282, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206488
https://doi.org/10.1115/SBC2009-206488
View Paper titled, Transmural Flow Bioreactor for Vascular Tissue Engineering
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Topics: Bioreactors, Flow (Dynamics), Tissue engineering, Biological tissues, Coronary arteries, Oxygen, Surgery
Proceedings Papers

CFD-Aided Design of a Dynamic Culture System for the Co-Culture of Adherent and Non-Adherent Cells

Marco Cantini, Gianfranco B. Fiore, Alberto Redaelli, Monica Soncini
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1067-1068, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206431
https://doi.org/10.1115/SBC2009-206431
View Paper titled, CFD-Aided Design of a Dynamic Culture System for the Co-Culture of Adherent and Non-Adherent Cells
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Topics: Bioreactors, Cancer, Computational fluid dynamics, Design, Dynamic systems, Fibers, Radiation therapy, Stem cells