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Proceedings Papers

Understanding Biological Structures Through Exploring the Mechanical Response of Cell-Like Systems

Ying Zhang, Philip R. LeDuc
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 401-402, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192679
https://doi.org/10.1115/SBC2008-192679
View Paper titled, Understanding Biological Structures Through Exploring the Mechanical Response of Cell-Like Systems
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Topics: Atomic force microscopy, Biological cells, Biology, Biotechnology, Cancer, Fluorescence, Laser scanning microscopy, Mechanical properties, Membranes, Physics
Proceedings Papers

A Hyperelastic Contact Model for the Indentation of Chondrocytes and Cartilage Extracellular Matrix

David C. Lin, David I. Shreiber, Emilios K. Dimitriadis, Ferenc Horkay
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1069-1070, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-191631
https://doi.org/10.1115/SBC2008-191631
View Paper titled, A Hyperelastic Contact Model for the Indentation of Chondrocytes and Cartilage Extracellular Matrix
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Topics: Cartilage, Chondrocytes, Atomic force microscopy, Elasticity, Biological tissues, Biomechanics, Diseases, Elastic moduli, Imaging, Microscale devices
Proceedings Papers

Mechanical Properties of TMJ Disc Cells Measured by Atomic Force Microscopy

Julie X. Yun, Lixia Zhang, Delphine Dean, Martine LaBerge, Hai Yao
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1075-1076, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193115
https://doi.org/10.1115/SBC2008-193115
View Paper titled, Mechanical Properties of TMJ Disc Cells Measured by Atomic Force Microscopy
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Topics: Atomic force microscopy, Disks, Mechanical properties, Bearings, Biological tissues, Lubrication, Physiology, Signals, Stress, Stress concentration
Proceedings Papers

The Dependence of Mechanical Properties of Adult Rat Myocytes on Cell Alignment

Honghai Liu, Julie X. Yun, Russel K. Pirlo, Delpine Dean, Hai Yao, Martine Laberge, Bruce Z. Gao
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 573-574, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193024
https://doi.org/10.1115/SBC2008-193024
View Paper titled, The Dependence of Mechanical Properties of Adult Rat Myocytes on Cell Alignment
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Topics: Mechanical properties, Biological tissues, Atomic force microscopy, Lasers, Damage, Junctions, Maintenance, Myocardium, Patient treatment, Stress
Proceedings Papers

Inhomogenous Stiffness of Articular Chondrocytes Measured by Atomic Force Microscopy

Nadeen O. Chahine, Todd A. Sulchek
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 319-320, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192500
https://doi.org/10.1115/SBC2008-192500
View Paper titled, Inhomogenous Stiffness of Articular Chondrocytes Measured by Atomic Force Microscopy
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Topics: Atomic force microscopy, Chondrocytes, Stiffness, Probes, Cartilage, Composite materials, Elastic moduli, Maintenance, Mechanical properties, Stress
Proceedings Papers

Alternative Splicing for Mechanical Resilience: The Softening Effect of Filamin’s Hinge

Dennis E. Discher, Colin Johnson
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 789-790, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176751
https://doi.org/10.1115/SBC2007-176751
View Paper titled, Alternative Splicing for Mechanical Resilience: The Softening Effect of Filamin’s Hinge
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Topics: Hinges, Resilience, Atomic force microscopy, Proteins, Chain, Dichroism (Pleochroism), Molecular mechanics, Stability
Proceedings Papers

Mesenchymal Stem Cell Injection After Myocardial Infarction Improves Myocardial Compliance

Dennis Discher, Adam Engler
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 249-250, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176754
https://doi.org/10.1115/SBC2007-176754
View Paper titled, Mesenchymal Stem Cell Injection After Myocardial Infarction Improves Myocardial Compliance
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Topics: Stem cells, Myocardium, Elasticity, Atomic force microscopy, Catheters, Coronary arteries, Electrical conductance, Geometry, Patient treatment, Preservation
Proceedings Papers

Elasticity of Cartilage Measured by Large Strain, Non-Hertzian AFM Nanoindentation

David C. Lin, Emilios K. Dimitriadis, Ferenc Horkay
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 945-946, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176618
https://doi.org/10.1115/SBC2007-176618
View Paper titled, Elasticity of Cartilage Measured by Large Strain, Non-Hertzian AFM Nanoindentation
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Topics: Atomic force microscopy, Cartilage, Elasticity, Nanoindentation, Contact mechanics, Elastic moduli, Geometry, Probes, Resolution (Optics), Spectroscopy
Proceedings Papers

Analysis of the Active Response of Cells to Cyclic Loading Using a Modified AFM System

P. Weafer, N. Reynolds, W. Ronan, E. Dowling, S. Jarvis, P. McGarry
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT35A005, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14793
https://doi.org/10.1115/SBC2013-14793
View Paper titled, Analysis of the Active Response of Cells to Cyclic Loading Using a Modified AFM System
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Topics: Atomic force microscopy, Deformation, Biological tissues, Maintenance, Osteoblasts, Tension, Testing
Proceedings Papers

The Effects of Extracellular Matrix Protein Insufficiency and Treatment on the Stiffness of Arterial Smooth Muscle Cells

Gabriela Espinosa, Lisa Bennett, William Gardner, Jessica Wagenseil
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT62A002, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14131
https://doi.org/10.1115/SBC2013-14131
View Paper titled, The Effects of Extracellular Matrix Protein Insufficiency and Treatment on the Stiffness of Arterial Smooth Muscle Cells
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Topics: Muscle, Proteins, Stiffness, Surface mount components, Mechanical properties, Atomic force microscopy, Elasticity, Fibers, Biological tissues, Cardiovascular system
Proceedings Papers

Understanding the Mechanical Properties of Microalgae Using Atomic Force Microscopy

Kristin M. Warren, Jeremiah Mpagazehe, C. Fred Higgs, III, Philip LeDuc
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT17A012, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14317
https://doi.org/10.1115/SBC2013-14317
View Paper titled, Understanding the Mechanical Properties of Microalgae Using Atomic Force Microscopy
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Topics: Atomic force microscopy, Mechanical properties, Energy generation, Force measurement, Mechanical behavior, Young's modulus
Proceedings Papers

A Novel Device for the Microindentation of Soft Biomaterials With Application to Aortic Valve Leaflets

Matthew G. Doyle, Moussa Chehade, Craig A. Simmons
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT04A023, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14733
https://doi.org/10.1115/SBC2013-14733
View Paper titled, A Novel Device for the Microindentation of Soft Biomaterials With Application to Aortic Valve Leaflets
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Topics: Biomaterials, Valves, Mechanical properties, Microscale devices, Atomic force microscopy, Compression, Nanoscale phenomena, Testing
Proceedings Papers

Simultaneous Determination of E, G and ν of Soft Hydrogels Using Theory of Elasticity

Uday Chippada, Xue Jiang, Lulu Li, Rene Schloss, Bernard Yurke, Noshir Langrana
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 939-940, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204684
https://doi.org/10.1115/SBC2009-204684
View Paper titled, Simultaneous Determination of E, G and ν of Soft Hydrogels Using Theory of Elasticity
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Topics: Elasticity, Hydrogels, Poisson ratio, Atomic force microscopy, Compression, Elastic moduli, Mechanical properties, Shear modulus, Stiffness
Proceedings Papers

Quantitative Mapping of Local Mechanical Properties of Living Cells at Near-Physiological Conditions Using Multi-Harmonic Atomic Force Microscopy

Alexander Cartagena, Wen-Horng Wang, Robert L. Geahlen, Arvind Raman
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 523-524, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80837
https://doi.org/10.1115/SBC2012-80837
View Paper titled, Quantitative Mapping of Local Mechanical Properties of Living Cells at Near-Physiological Conditions Using Multi-Harmonic Atomic Force Microscopy
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Topics: Atomic force microscopy, Biological cells, Mechanical properties, Physiology, Biomechanics, Assaying, Biology, Displacement, Resolution (Optics), Underpinning
Proceedings Papers

Characterization of the Elasticity of Valve Interstitial Cells on Soft Substrates Using Atomic Force Microscopy

Haijiao Liu, Craig A. Simmons, Yu Sun
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 831-832, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80369
https://doi.org/10.1115/SBC2012-80369
View Paper titled, Characterization of the Elasticity of Valve Interstitial Cells on Soft Substrates Using Atomic Force Microscopy
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Topics: Atomic force microscopy, Elasticity, Valves, Glass, Mechanical properties, Diseases, Physiology, Stiffness
Proceedings Papers

Mechanical Response of Rat Cortical Neurons: AFM Indentations and Preliminary Modeling

Kristin Bernick, Thibault Prévost, Simona Socrate, Subra Suresh
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1031-1032, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206207
https://doi.org/10.1115/SBC2009-206207
View Paper titled, Mechanical Response of Rat Cortical Neurons: AFM Indentations and Preliminary Modeling
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Topics: Atomic force microscopy, Damage, Design, Explosions, Gears, Improvised explosive devices, Land mines, Modeling, Rockets, Soldiers
Proceedings Papers

Surface and Bulk Stiffness of the Mature Porcine Cartilage-Like Tissue Repaired With a Scaffold-Free, Stem Cell-Based Tissue Engineered Construct (TEC)

Ryosuke Nansai, Mamoru Ogata, Junichi Takeda, Wataru Ando, Norimasa Nakamura, Hiromichi Fujie
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 735-736, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204404
https://doi.org/10.1115/SBC2009-204404
View Paper titled, Surface and Bulk Stiffness of the Mature Porcine Cartilage-Like Tissue Repaired With a Scaffold-Free, Stem Cell-Based Tissue Engineered Construct (TEC)
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Topics: Biological tissues, Cartilage, Stiffness, Thermoelectric coolers, Atomic force microscopy, Maintenance, Patient treatment, Safety, Stem cells, Tissue engineering
Proceedings Papers

Hybrid Computational Methods for Analysis of AFM Indentation on Mechanically Heterogeneous Samples

Evren U. Azeloglu, Gaurav Kaushik, Kevin D. Costa
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 557-558, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206433
https://doi.org/10.1115/SBC2009-206433
View Paper titled, Hybrid Computational Methods for Analysis of AFM Indentation on Mechanically Heterogeneous Samples
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Topics: Atomic force microscopy, Computational methods, Biological tissues, Composite materials, Finite element analysis, Materials properties, Mechanical properties, Micromechanics (Engineering), Modeling, Stress
Proceedings Papers

The Inhomogeneous Mechanical Properties of the Pericellular Matrix of Articular Cartilage Measured In Situ by Atomic Force Microscopy

Rebecca E. Wilusz, Eric M. Darling, Michael P. Bolognesi, Stefan Zauscher, Farshid Guilak
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1065-1066, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206403
https://doi.org/10.1115/SBC2009-206403
View Paper titled, The Inhomogeneous Mechanical Properties of the Pericellular Matrix of Articular Cartilage Measured In Situ by Atomic Force Microscopy
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Topics: Atomic force microscopy, Cartilage, Mechanical properties, Chondrocytes, Biomechanics, Bearings, Biological tissues, Friction, Resolution (Optics), Stress
Proceedings Papers

Tribological Properties of Hip Implant From Atomic Force Microscopy

CongTruyen Duong, JunDong Chang, SangSoo Lee, Seonghun Park
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 699-700, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206227
https://doi.org/10.1115/SBC2009-206227
View Paper titled, Tribological Properties of Hip Implant From Atomic Force Microscopy
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Topics: Atomic force microscopy, Hip joint prostheses, Tribology, Metals, Wear, Surface roughness, Microscale devices, Carbon, Cobalt, Diamonds