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Proceedings Papers

Proliferation and Fiber Formation of Human Dermal Fibroblasts on Patterned Differentially Adherent Substrates

Nathan R. Schiele, Douglas B. Chrisey, David T. Corr
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 517-518, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192910
https://doi.org/10.1115/SBC2008-192910
View Paper titled, Proliferation and Fiber Formation of Human Dermal Fibroblasts on Patterned Differentially Adherent Substrates
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Topics: Fibers, Fibroblasts, Biological tissues, Soft tissues, Agar, Geometry, Lasers, Micromachining, Skin, Tissue engineering
Proceedings Papers

Time-Resolved Study of Laser-Induced Bubbles and Shockwaves in Agar Gel Tissue Phantoms

Francisco Pérez-Gutiérrez, Rodger Evans, Santiago Camacho-López, Guillermo Aguilar
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 613-614, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193061
https://doi.org/10.1115/SBC2008-193061
View Paper titled, Time-Resolved Study of Laser-Induced Bubbles and Shockwaves in Agar Gel Tissue Phantoms
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Topics: Agar, Biological tissues, Bubbles, Lasers, Phantoms, Shock waves, Heating, Absorption, Biomedicine, Damage
Proceedings Papers

Cyclic Compression of Chondrocytes Counteracts Pro-Inflammatory Tissue Remodeling Induced by Interleukin-1

A. E. DiTullio, S. Park, P. A. Torzilli, C. T. Chen
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 93-94, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193027
https://doi.org/10.1115/SBC2008-193027
View Paper titled, Cyclic Compression of Chondrocytes Counteracts Pro-Inflammatory Tissue Remodeling Induced by Interleukin-1
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Topics: Biological tissues, Chondrocytes, Compression, Agar, Maintenance, Physiology, Shear (Mechanics), Wounds
Proceedings Papers

Influence of Nutrient Channels on Development of Engineered Cartilage Properties

Liming Bian, Kenneth W. Ng, Eric G. Lima, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1055-1056, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176234
https://doi.org/10.1115/SBC2007-176234
View Paper titled, Influence of Nutrient Channels on Development of Engineered Cartilage Properties
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Topics: Agar, Cartilage, Chondrocytes, Diffusion (Physics), Dimensions, Materials properties, Mechanical properties
Proceedings Papers

Fickian Behavior and Concentration-Dependence of the Diffusion of Dextran in Agarose

Michael B. Albro, Vikram Rajan, Clark T. Hung, Gerard A. Ateshian
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1061-1062, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176646
https://doi.org/10.1115/SBC2007-176646
View Paper titled, Fickian Behavior and Concentration-Dependence of the Diffusion of Dextran in Agarose
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Topics: Agar, Diffusion (Physics), Biological tissues, Cartilage, Chondrocytes, Dynamic testing (Materials), Fluorescence, Macromolecules, Mechanical properties, Soft tissues
Proceedings Papers

Sliding Contact Modulates ECM Expression in Chondroctye-Laden Agarose Gels

Alice H. Huang, Robert L. Mauck
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1011-1012, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176427
https://doi.org/10.1115/SBC2007-176427
View Paper titled, Sliding Contact Modulates ECM Expression in Chondroctye-Laden Agarose Gels
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Topics: Agar, Anisotropy, Bearings, Biological tissues, Bioreactors, Cartilage, Chondrocytes, Diseases, Friction, Hydrogels
Proceedings Papers

Effect of Age and Frequency on Intervertebral Disc Cell Response to Dynamic Compression

Casey L. Korecki, Catherine K. Kuo, Rocky S. Tuan, James C. Iatridis
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 825-826, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176595
https://doi.org/10.1115/SBC2007-176595
View Paper titled, Effect of Age and Frequency on Intervertebral Disc Cell Response to Dynamic Compression
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Topics: Compression, Intervertebral discs, Biological tissues, Chondrocytes, Hydrostatics, Stress, Agar, Annulus, Fibroblasts, Mechanobiology
Proceedings Papers

The Response of Tissue Engineered Cartilage to the Temporal Application of Transforming and Insulin-Like Growth Factors

Christopher J. O’Conor, Kenneth W. Ng, Lindsay E. Kugler, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1023-1024, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176523
https://doi.org/10.1115/SBC2007-176523
View Paper titled, The Response of Tissue Engineered Cartilage to the Temporal Application of Transforming and Insulin-Like Growth Factors
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Topics: Biological tissues, Cartilage, Tissue engineering, Agar, Biocompatibility, Chondrocytes, Mechanical properties
Proceedings Papers

Scaffold Properties Play a Critical Role in the Retention of Synthesized Glycosaminoglycans in Tissue Engineered Cartilage

Lindsay E. Kugler, Kenneth W. Ng, Christopher J. O’Conor, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1031-1032, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176558
https://doi.org/10.1115/SBC2007-176558
View Paper titled, Scaffold Properties Play a Critical Role in the Retention of Synthesized Glycosaminoglycans in Tissue Engineered Cartilage
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Topics: Biological tissues, Cartilage, Agar, Tissue engineering, Chondrocytes, Diffusion (Physics), Explosives, Maintenance, Physiology, Testing
Proceedings Papers

An in Situ Dual Indentation and Optimization Method to Determine Mechanical Properties of Articular Cartilage

Jonathan E. Pottle, J.-K. Francis Suh
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 941-942, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176601
https://doi.org/10.1115/SBC2007-176601
View Paper titled, An in Situ Dual Indentation and Optimization Method to Determine Mechanical Properties of Articular Cartilage
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Topics: Cartilage, Mechanical properties, Optimization, Compression, Relaxation (Physics), Stress, Agar, Biological tissues, Biomechanics, Creep
Proceedings Papers

Chondrocytes and Fibrochondrocytes Differentially Process Aggrecan During De Novo Extracellular Matrix Assembly

Christopher G. Wilson, Marc E. Levenston
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1041-1042, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176669
https://doi.org/10.1115/SBC2007-176669
View Paper titled, Chondrocytes and Fibrochondrocytes Differentially Process Aggrecan During De Novo Extracellular Matrix Assembly
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Topics: Chondrocytes, Manufacturing, Biological tissues, Materials properties, Agar, Cartilage, Proteins, Stiffness
Proceedings Papers

Novel Hyaluronic Acid Nanocomposite Hydrogel for Cartilage Tissue Engineering: Utilizing Yield Stress for Ease of Implantation

Emily Beck, Cory Berkland, Stevin Gehrke, Michael Detamore
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT48A003, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14350
https://doi.org/10.1115/SBC2013-14350
View Paper titled, Novel Hyaluronic Acid Nanocomposite Hydrogel for Cartilage Tissue Engineering: Utilizing Yield Stress for Ease of Implantation
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Topics: Cartilage, Hydrogels, Nanocomposites, Tissue engineering, Yield stress, Agar, Arthroplasty, Biocompatibility, Biodegradation, Biological tissues
Proceedings Papers

Chondrocytes in Agarose: Cell Damage and the Pericellular Matrix

Mark C. van Turnhout, Stefan A. H. de Vries, Corrinus C. van Donkelaar, Cees W. J. Oomens
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT55A017, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14458
https://doi.org/10.1115/SBC2013-14458
View Paper titled, Chondrocytes in Agarose: Cell Damage and the Pericellular Matrix
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Topics: Agar, Chondrocytes, Damage, Cartilage, Maintenance, Biological tissues
Proceedings Papers

The Role of Agarose Mechanical Response on the Matrix Synthesis of Nucleus Pulposus Cells: A Pilot Study

Arzu Tasci, Ladina Ettinger, Stephen Ferguson, Philippe Büchler
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 561-562, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206763
https://doi.org/10.1115/SBC2009-206763
View Paper titled, The Role of Agarose Mechanical Response on the Matrix Synthesis of Nucleus Pulposus Cells: A Pilot Study
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Topics: Agar, Intervertebral discs, Maintenance, Mechanical properties, Signals, Stress
Proceedings Papers

The Mechanical Behavior of Engineered Hydrogels

Audrey L. Earnshaw, Justine J. Roberts, Garret D. Nicodemus, Stephanie J. Bryant, Virginia L. Ferguson
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1197-1198, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206705
https://doi.org/10.1115/SBC2009-206705
View Paper titled, The Mechanical Behavior of Engineered Hydrogels
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Topics: Hydrogels, Mechanical behavior, Agar, Tissue engineering, Biological tissues, Biomaterials, Chain, Chondrocytes, Polymerization
Proceedings Papers

Dynamic Compressive Loading and Crosslinking Density Influence the Chondrogenic and Hypertrophic Differentiation of Human Mesenchymal Stem Cells Seeded in Hyaluronic Acid Hydrogels

Liming Bian, Robert L. Mauck, Jason A. Burdick
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 383-384, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80048
https://doi.org/10.1115/SBC2012-80048
View Paper titled, Dynamic Compressive Loading and Crosslinking Density Influence the Chondrogenic and Hypertrophic Differentiation of Human Mesenchymal Stem Cells Seeded in Hyaluronic Acid Hydrogels
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Topics: Density, Hydrogels, Stem cells, Cartilage, Agar, Biological tissues, Chondrocytes, Compression, Design, Electromagnetic induction
Proceedings Papers

Strains in Stratified Agarose Constructs as Determined by Displacement-Encoded MRI

Adam Griebel, C. C. van Donkelaar, Corey P. Neu
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 385-386, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80143
https://doi.org/10.1115/SBC2012-80143
View Paper titled, Strains in Stratified Agarose Constructs as Determined by Displacement-Encoded MRI
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Topics: Agar, Displacement, Magnetic resonance imaging, Biological tissues, Cartilage, Chondrocytes, Cylinders, Diseases, Glass, Maintenance
Proceedings Papers

Influence of Chondrocyte Zone on Co-Cultures With Mesenchymal Stem Cells in HA Hydrogels for Cartilage Tissue Engineering

Minwook Kim, Jason A. Burdick, Robert L. Mauck
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 391-392, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80859
https://doi.org/10.1115/SBC2012-80859
View Paper titled, Influence of Chondrocyte Zone on Co-Cultures With Mesenchymal Stem Cells in HA Hydrogels for Cartilage Tissue Engineering
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Topics: Cartilage, Chondrocytes, Hydrogels, Stem cells, Tissue engineering, Bone, Agar, Biological tissues, Mechanical properties, Proteins
Proceedings Papers

Elucidation of Microstructural Interactions Between Collagen and Non-Fibrillar Matrix in Soft Tissue Using a Coupled Fiber-Matrix Model

Lijuan Zhang, Spencer P. Lake, Victor K. Lai, Victor H. Barocas, Mark S. Shephard
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 167-168, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80401
https://doi.org/10.1115/SBC2012-80401
View Paper titled, Elucidation of Microstructural Interactions Between Collagen and Non-Fibrillar Matrix in Soft Tissue Using a Coupled Fiber-Matrix Model
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Topics: Fibers, Soft tissues, Biological tissues, Stress, Agar, Composite materials, Damage, Diseases, Mechanical properties, Microscale devices
Proceedings Papers

Insulin and Ascorbate Have a Much Greater Influence Than Transferrin and Selenous Acid on the Growth of Engineered Cartilage in Chondrogenic Media

Alexander D. Cigan, Robert J. Nims, Michael B. Albro, Sarah L. Breves, Clark T. Hung, Gerard A. Ateshian
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1141-1142, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80572
https://doi.org/10.1115/SBC2012-80572
View Paper titled, Insulin and Ascorbate Have a Much Greater Influence Than Transferrin and Selenous Acid on the Growth of Engineered Cartilage in Chondrogenic Media
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Topics: Cartilage, Chondrocytes, Agar, Biological tissues, Mechanical properties, Modeling, Osteoarthritis, Tissue engineering