Flow Diverted Aneurysmal Hemodynamic Simulations and Validation With Experiments

Brain aneurysms occur due to abnormal ballooning of cerebral arteries. Rupture of the cerebral aneurysms can result in subarachnoid hemorrhage and may prove fatal for patients [1]. Surgical clipping is a highly invasive option for treatment of aneurysms. Endovascular flow diverting stents have recently emerged as a less invasive treatment for cerebral aneurysms. Flow diverters for intracranial aneurysms, are porous metallic mesh tubes deployed across the neck of the aneurysm to exclude the aneurysm from the circulation [2–4]. By producing a substantial reduction of flow inside the aneurysm and by promoting activation of platelets that cross the device into the aneurysm, intra-aneurysmal thrombus is generated and the aneurysm is eventually excluded from the circulation.