An in-vitro system was developed to mimic the impact deceleration and strain associated with concussive injuries. Similar in concept to a full scale crash test, the bench top concussive bioreactor can deliver decelerations from 0–250 g and biaxial strains from 5–25% to cells in culture. We are not aware of another system like this. From cellular testing, an injury threshold of 100g combined with 10% strain was identified. These values appear consistent with human brain injury data.

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