The microgravity environment encountered during spaceflight has numerous deleterious effects on the human body, with one of the most drastic being decreased bone mass due to mechanical unloading. These alterations in bone mass and skeletal strength are one of the foremost limitations of future space exploration. Due to the cost of long-duration space missions, it is critically important to develop ground-based models of the microgravity environment encountered during spaceflight to investigate possible countermeasures to maintain skeletal integrity.

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