The initiation and progression of hip osteoarthritis (OA) may be predicted by mechanical factors . Contact stress (CS), maximum shear stress (MSS) at the osteochondral interface and first principal strain (FPS) at the articular surface have been identified as parameters that alter the physical integrity and metabolism of cartilage . Although these parameters are difficult to measure in-vivo, they can be predicted using finite element (FE) models. However, the reliability of model predictions and the effects of model assumptions are largely unknown. Direct validation of FE models against experimental measurements for a series of specimens shows the reliability of predictions across specimen geometry , although to date this has only been performed for a single hip .
- Bioengineering Division
Effects of Cartilage Constitutive Model on Specimen-Specific Validation and Predictions of Cartilage Mechanics in the Human Hip
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Henak, CR, Kapron, AL, Anderson, AE, Ateshian, GA, Ellis, BJ, Maas, SA, & Weiss, JA. "Effects of Cartilage Constitutive Model on Specimen-Specific Validation and Predictions of Cartilage Mechanics in the Human Hip." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions. Sunriver, Oregon, USA. June 26–29, 2013. V01BT47A003. ASME. https://doi.org/10.1115/SBC2013-14132
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