Role of Glycosaminoglycans in the Mechanical Behavior of the Posterior Sclera

Changes in sclera mechanical properties have been shown to play an important role in ocular diseases such as glaucoma ^1,2,3 and myopia ^4,5. In both diseases, those changes in mechanical behavior were observed along with changes in proteoglycan (PG) and associated glycosaminoglycan (GAG) levels, which have been shown to significantly influence the viscoelastic behavior of other tissues ⁶.