Magnetic nanoparticles are currently under intense investigation as a heating strategy for hyperthermia cancer treatment because they are promising as a means to target the heating specifically to the tumor.[1–4] Currently, our ability to create practical and useful numerical models in dimensional spaces similar to ordinary small tumors is severely hampered by the multiple orders of magnitude of the relative scales: nm to mm. Consequently, the preponderance of literature on the topic describes experimental studies only. Detailed individual nanoparticle model spaces with moderate dimensions up to mm would be nearly intractably computationally intensive, requiring peta-scale computing resources. It would advance the state of the art to be able to apply practical computing machinery to analyze realistic medium scale in vivo systems. Such a tool could be reasonably applied in experimental analysis, and potentially in treatment planning and assessment.

This content is only available via PDF.
You do not currently have access to this content.