Cerebrospinal fluid (CSF) is produced at a constant rate in the choroid plexuses of the lateral and third ventricles, and it predominately drains through the Sylvius aqueduct to the fourth ventricle. If the Sylvius aqueduct becomes obstructed, such as caused by a growing tumor adjacent to it, CSF accumulates in the ventricles and the ventricles expand significantly, leading to a medical condition known as noncommunicating, hydrocephalus.
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A Flow-Controlled Finite Element Model of Noncommunicating Hydrocephalus
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Hendra, WR, Lefever, JA, García, JJ, & Smith, JH. "A Flow-Controlled Finite Element Model of Noncommunicating Hydrocephalus." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions. Sunriver, Oregon, USA. June 26–29, 2013. V01BT36A001. ASME. https://doi.org/10.1115/SBC2013-14058
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