Development of a Traumatic Anterior Cruciate Ligament and Meniscal Rupture Model to Study Osteoarthritis

Participation in sports, recreation, and exercise is progressively gaining more popularity in American culture and, along with it, the risk of acute and chronic injuries. People who injure a knee before the age of 22 have a greater than 3-fold risk of developing osteoarthritis (OA) in the injured joint by their mid 50s ⁵. Specifically, anterior cruciate ligament (ACL) and meniscal injuries are strongly associated with the development of OA ⁴, a common and widespread musculoskeletal disease ¹.