Most previous research on engineered microvessels has been in isotropic systems;1–3 however, aligned microvessels would be advantageous both in terms of mimicking alignment in native tissue (e.g. myocardium4), and in terms of establishing efficient perfusion of the microvessels, as alignment creates natural inlet and outlet sides.
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Engineered Microvessels Subjected to Interstitial Flow
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Morin, KT, Dries-Devlin, JL, & Tranquillo, RT. "Engineered Microvessels Subjected to Interstitial Flow." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT22A005. ASME. https://doi.org/10.1115/SBC2013-14701
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