Carotid artery stenting (CAS) is relatively new procedure introduced to treat severe carotid atherosclerotic disease for high risk patient categories. The advantages of this technique are its minimal invasiveness, easiness of the procedure and the short hospitalization compared to surgical option. However, perioperative complications, such as stroke, can lead to failure of the procedure and long terms effects of the procedure are not completely understood. It is not unrealistic to assume that the mechanical changes of the pathophysiological environment at the stented vessel can induce tissue damage and promote remodeling and restenosis but how these factor (inter)act is still a matter of debate.

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