Calcific aortic valve disease (CAVD) is the most prevalent heart valve disease in the U.S. and is characterized by the formation of calcific lesions within the valve leaflets . The emerging hemodynamic theory of CAVD pathogenesis assumes a link between gradual hemodynamic alterations caused by the growing lesions and further disease progression [2–5]. In order to test this hypothesis, it is necessary to quantify the hemodynamic changes experienced downstream of a calcifying valve.
- Bioengineering Division
Development of a Laboratory Model of Aortic Valve Calcification
Biddle, S, Seaman, C, & Sucosky, P. "Development of a Laboratory Model of Aortic Valve Calcification." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT20A013. ASME. https://doi.org/10.1115/SBC2013-14270
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