Accumulated experience using flow diverters in humans suggests that complete cure of the aneurysm is usually a protracted process that can last up to twelve months [1]. While it is well established that a properly designed flow diverter serves as a scaffold for neointimal proliferation, the process of its formation over the aneurysm neck is delayed until the aneurysm cavity itself is occluded by a thrombus, negating flow of fresh blood through the neck, and thus allowing the neointimal formation to bridge the aneurysm neck. The notion that induction of some injury to the luminal surface of the aneurysmal tissue, particularly to the endothelium, may result in a healing response that is faster than just placing a flow diverter and waiting for thrombus formation within the aneurysm has been tried in the past using various experimental models. Some of the injuries to the aneurysm tissue that have been tried in the past include mechanical scraping, thermal heating and UV irradiation. All these attempts, while showing that hastening the thrombus formation is feasible, have not resulted in any success due to the fact that the processes that were tried suffered from lack of proper control to be implemented in actual aneurysmal tissue that is weakened and diseased a priori.

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