Windpipe defects result in decreased quality of life for the patient, making breathing, speaking, and swallowing difficult. Disorders of the trachea requiring intervention methods not adequately treated by slide tracheoplasty or cartilage augmentation necessitate the use of prosthetic material to expand the trachea. Furthermore, some donor site morbidity occurs with augmentation techniques and size or shape mismatches are not uncommon. Tissue engineering has the potential to create effective replacement trachea-like tissue for procedures like laryngotracheal reconstruction and may circumvent these problems.
- Bioengineering Division
Material Composition Gradients and Protein Release for Tracheal Defect Repair
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Ott, L, Vu, C, Farris, A, Weatherly, R, & Detamore, M. "Material Composition Gradients and Protein Release for Tracheal Defect Repair." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT17A015. ASME. https://doi.org/10.1115/SBC2013-14391
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