Fine anatomical structures, including nerve roots and denticulate ligaments, can significantly influence cerebrospinal fluid (CSF) dynamics inside the spinal subarachnoid space (SSS). In this study, we completed computational fluid dynamics (CFD) simulations based on subject specific geometries of the cervical spine with and without idealized fine structures (nerve roots and denticulate ligaments, NRDL). The results show that NRDL had a significant impact on CSF dynamics in terms of velocity distribution, flow streamlines, bidirectional nature of the flow and the pressure drop.
- Bioengineering Division
Cerebrospinal Fluid Dynamics in the Cervical Spine: Importance of Fine Anatomical Structures
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Pahlavian, SH, Yiallourou, TI, Tubbs, RS, Bunck, A, Goodin, M, Loth, F, Raisee, M, & Martin, BA. "Cerebrospinal Fluid Dynamics in the Cervical Spine: Importance of Fine Anatomical Structures." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT13A020. ASME. https://doi.org/10.1115/SBC2013-14537
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