Coating vaginal or rectal epithelium using microbicidal gels is a promising preventive procedure against HIV and other sexually transmitted infections (STIs). A microbicidal gel is deployed as a delivery vehicle of anti-HIV and other anti-STI agents and it is also used to act as barrier between the pathogens and the biological tissue. The efficacy of a microbicidal gel depends greatly on the extent of the spreading and the amount of the epithelial surfaces covered.
- Bioengineering Division
The Impact of Tissue Viscoelasticity on the Flow Dynamics of an Anti-HIV Microbicidal Gel: Numerical Simulations
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Talbi, Z, & Kieweg, SL. "The Impact of Tissue Viscoelasticity on the Flow Dynamics of an Anti-HIV Microbicidal Gel: Numerical Simulations." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT05A004. ASME. https://doi.org/10.1115/SBC2013-14116
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