Intracranial aneurysms affect thousands of people every year, therefore the ability to monitor their growth or predict their rupture would be invaluable for planning treatment. One proposed method to address this issue of predicting rupture is to use computational fluid dynamics (CFD) based on phase contrast magnetic resonance (PC-MR). CFD and PCMR have been used to understand some of the fundamental conditions of cerebrovascular flow. While there has been general acceptance of the validity of CFD, some research suggests that there can be poor correlation between CFD flow calculations and directly measured flow (1). Previous research has qualitatively compared CFD to PC-MR and demonstrated similar pathlines (2). To the authors’ knowledge a systematic quantitative comparison has not been preformed. Therefore the purpose of this work is to quantitatively compare velocity data from phase-contrast MRI measurements and from a CFD model derived from MRI geometry and flow boundary conditions in an in-vitro aneurysm model.

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