Arteries exhibit a complex mechanical behavior due to their complex structure and composition. When smooth muscle cells (SMCs) are stimulated to contract, an artery constricts and develops the so called active stress in the arterial wall. Assuming that the SMCs are oriented in the circumferential direction most of studies consider solely development of the circumferential active stress [1]. However, histological findings show existence of SMCs oriented in both the circumferential and axial direction; these vessels manifest biaxial contractile response [2, 3]. In this study we also observed biaxial contractile response and processed the experimental data to incorporate an active axial stress in the constitutive formulation of the arterial tissue.
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ASME 2012 Summer Bioengineering Conference
June 20–23, 2012
Fajardo, Puerto Rico, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4480-9
PROCEEDINGS PAPER
Active Axial Stress in Mouse Aorta
Aristotelis Agianniotis,
Aristotelis Agianniotis
École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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Alexander Rachev,
Alexander Rachev
University of South Carolina, Columbia, SC
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Nikos Stergiopulos
Nikos Stergiopulos
École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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Aristotelis Agianniotis
École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
Alexander Rachev
University of South Carolina, Columbia, SC
Nikos Stergiopulos
École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
Paper No:
SBC2012-80102, pp. 975-976; 2 pages
Published Online:
July 19, 2013
Citation
Agianniotis, A, Rachev, A, & Stergiopulos, N. "Active Axial Stress in Mouse Aorta." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 975-976. ASME. https://doi.org/10.1115/SBC2012-80102
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