Traumatic brain injury (TBI) can result from blunt force trauma, rapid inertial loading, or extracranial pressure (i.e., explosive blast). Much of the pathway between mechanical insult and neurological injury remains unclear, in part because data on the mechanical response of the brain are difficult to acquire in vivo. The physics of measuring harmonically-varying displacement fields in vivo using motion-sensitive magnetic resonance imaging (MRI) is well understood [1], yet to date data in the human brain have not been investigated in terms of strain and rotation. Here these kinematic quantities are examined and new light is shed on biomechanics of the living intact human brain as it is subjected to harmonic acoustic pressure load.

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