Quantitative computed tomography (QCT)-based finite element (FE) models provide better predictions of vertebral strength compared to traditional methods currently used in clinical diagnosis . In QCT-based FE models, the intra- and inter-specimen variations in trabecular anisotropy are often ignored, despite evidence that the biomechanical behavior of the vertebra depends on the architecture of the vertebral trabecular bone . A realistic representation of the specimen-specific, trabecular anisotropy in the FE models of vertebrae would potentially improve predictions of vertebral failure. The overall goal of this study was to evaluate the importance of incorporating specimen-specific, trabecular anisotropy for QCT-based FE predictions of vertebral stiffness and deformation patterns. The major aims of this study were (a) to compare the QCT-based FE results obtained with a constant, anisotropic, material model (the “generic-anisotropic” model) for trabecular bone to those obtained with a specimen-specific, anisotropic, material model and (b) to study the influence of degree of anisotropy (DA) on the FE predictions of vertebral stiffness.
- Bioengineering Division
Influence of Specimen-Specific Trabecular Anisotropy on QCT-Based Finite Element Analyses of Lumbar Vertebra
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Unnikrishnan, GU, Barest, GD, Berry, DB, Hussein, AI, & Morgan, EF. "Influence of Specimen-Specific Trabecular Anisotropy on QCT-Based Finite Element Analyses of Lumbar Vertebra." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 537-538. ASME. https://doi.org/10.1115/SBC2012-80114
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