Lymphatic filariasis, a parasitic disease often resulting in severe lymphatic dysfunction and lymphedema, is perpetuated by an invasion of worms, delivered through mosquito bites, that reside, mature, and reproduce in the human lymphatic system. The disease cycle begins with stage 3 larvae (L3) leaving the mosquito and penetrating the dermal layer of the human while the mosquito is feeding where it eventually makes its way to a collecting lymphatic vessel where it resides for its adult life (up to 10 years) [1]. While many infected individuals will remain asymptomatic, a subset of patients will develop reconstruction of the tissue structure and the extreme swelling of the arms, legs, genitals and/or breasts. This elephantiasis occurs in over 10 million people worldwide and has a harsh negative effect on the infected individual’s ability to work and function in society.
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ASME 2012 Summer Bioengineering Conference
June 20–23, 2012
Fajardo, Puerto Rico, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4480-9
PROCEEDINGS PAPER
Design of an In Vitro Migration Chamber for Quantifying the Homing Patterns of Parasitic Worms
Kevin D. Parsons,
Kevin D. Parsons
Georgia Institute of Technology, Atlanta, GA
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Timothy Kassis,
Timothy Kassis
Institute of Bioengineering and Bioscience, Atlanta, GA
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J. Brandon Dixon
J. Brandon Dixon
Georgia Institute of Technology, Atlanta, GA
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Kevin D. Parsons
Georgia Institute of Technology, Atlanta, GA
Timothy Kassis
Institute of Bioengineering and Bioscience, Atlanta, GA
J. Brandon Dixon
Georgia Institute of Technology, Atlanta, GA
Paper No:
SBC2012-80711, pp. 247-248; 2 pages
Published Online:
July 19, 2013
Citation
Parsons, KD, Kassis, T, & Dixon, JB. "Design of an In Vitro Migration Chamber for Quantifying the Homing Patterns of Parasitic Worms." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 247-248. ASME. https://doi.org/10.1115/SBC2012-80711
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