Mitral valve is a two-leaflet valve that is located between the left atrium and the left ventricle of the heart. In order to successfully replace or repair mitral valve and develop effective prosthetic devices, it is critical to understand the in vivo mechanics of the normal mitral valve. Although research has been conducted to investigate animal mitral valve strains by in vivo experiments, it is still very challenging to obtain accurate in vivo stress and strain information of the human mitral valve.

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