Coronary and peripheral artery diseases are a leading cause of morbidity and mortality in developed countries. For severe cases, surgical intervention to bypass the disease using autologous vessels continues to be the preferred choice of treatment. These bypass vessels are typically obtained from the venous vasculature. Despite the superior long-term patency of veins over synthetic grafts, one-year failure rates approach 30–40% in both the coronary and peripheral systems [1–2]. Still, bypass surgery remains the recommended therapy for most persons with severe arterial blockages . As the number of bypass procedures increase and patients receiving bypasses live longer, improving the lifetime of bypass grafts is increasingly important.
- Bioengineering Division
Diameter Constriction Reduces Intramural Circumferential Stress Gradient in the Vein Under Arterial Pressures
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Wang, R, Gleason, RL, Jr., & Brewster, L. "Diameter Constriction Reduces Intramural Circumferential Stress Gradient in the Vein Under Arterial Pressures." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 1335-1336. ASME. https://doi.org/10.1115/SBC2012-80797
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