This research investigates the effect of pressure oscillation (PO) on the alveoli surface tension. Experimental and modeling simulations are used to show that introducing superimposed oscillations on the tidal volume excursion between 0–70Hz in a surfactant bubble lowers interfacial surface tension below values observed using tidal volume excursion alone. Evidently this makes it easier for an infant with RDS to maintain the required level of functional residual capacity without collapse.
- Bioengineering Division
Reduction of Alveoli Surface Tension Using Pressure Oscillation
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Al-Jumaily, AM, & Reddy, PI. "Reduction of Alveoli Surface Tension Using Pressure Oscillation." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 1257-1258. ASME. https://doi.org/10.1115/SBC2012-80082
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