During leukocyte rolling on the endothelium, membrane tethers can be extracted simultaneously from both leukocytes and endothelial cells because of the force imposed by the blood flow . Tether extraction has been shown to stabilize leukocyte rolling by increasing the lifetime of the adhesive selectin-ligand bonds that mediate leukocyte rolling . Over the past two decades, tether extraction has been studied extensively, both experimentally and theoretically. In contrast, much less is known about tether retraction.
- Bioengineering Division
Cellular Membrane Tether Retraction: Experiment and Model
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Shao, J, & Liu, B. "Cellular Membrane Tether Retraction: Experiment and Model." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 1163-1164. ASME. https://doi.org/10.1115/SBC2012-80760
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