Fibrillar collagens are an integral structural element of tissues throughout the body and help provide tensile strength. These collagens are highly resistant to degradation other than by a small number of collagenolytic enzymes. Examples of tensile mechanical forces in vivo include expansion and contraction of blood vessels, tension on tendons and ligaments, and compression and swelling of cartilage.
- Bioengineering Division
Covalent Cross-Linking Accelerates Collagen Enzyme Mechano-Kinetic Cleavage: Nanomechanics Predicts Microscale Behavior
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Bourne, JW, Lippell, JM, & Torzilli, PA. "Covalent Cross-Linking Accelerates Collagen Enzyme Mechano-Kinetic Cleavage: Nanomechanics Predicts Microscale Behavior." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 1157-1158. ASME. https://doi.org/10.1115/SBC2012-80392
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