High prevalence of osteoarthritis and poor intrinsic healing capacity of articular cartilage create a demand for cell-based strategies for cartilage repair. It is possible to tissue engineer cartilage with almost native proteoglycan content, but collagen reaches only 15% to 35% of the native content. Also its natural structural organization is not reproduced. These drawbacks contribute to its insufficient load-bearing properties.
Volume Subject Area:Poster Session I: Musculoskeletal Tissue Engineering
Topics:Agar, Cartilage, Bearings, Biological tissues, Engineers, Maintenance, Osteoarthritis, Stress
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