The mechanical properties of the microstructures surrounding cells influence the behavior of cells in differentiation, proliferation, and apoptosis, etc. The stiffness of the extra-cellular microenvironment has been shown to be one such mechanical property . Studies reported in the literature concerning the stiffness of the extracellular microenvironment mainly sought to understand the scientific principles and mechanisms underlying its effect on cell-environment interaction . This paper describes an approach that achieves such manipulation, and reports experimental results that demonstrate the effectiveness of this proposed approach.
- Bioengineering Division
Active Manipulation of ECM Stiffness
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Chen, PCY, Herath, SCB, Wang, D, Su, K, Liao, K, & Asada, H. "Active Manipulation of ECM Stiffness." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 869-870. ASME. https://doi.org/10.1115/SBC2011-53090
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