Assessments of regional heart wall deformation (wall motion, thickening, strain) are commonly used to evaluate left ventricular wall function in the clinical setting. Nuclear based imaging modalities such as PET and SPECT are commonly used to localize ischemic myocardial disease, and can identify impairment of cardiac function due to hypertrophic or dilated cardiomyopathies. Regional wall motion analysis in conjunction with global left ventricular (LV) ejection fraction is commonly used to assess systolic and diastolic function. The quantification of ventricular strains throughout the entire cardiac cycle provides valuable information that could be used to more effectively differentiate between diastolic and systolic dysfunction, as well as a more complete picture of overall cardiac performance.
- Bioengineering Division
Full Cardiac Cycle Strain Measurement Using Hyperelastic Warping, Application to Detecting Myocardial Dysfunction in Rat microPET Images
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Farrar, GE, Gullberg, GT, & Veress, AI. "Full Cardiac Cycle Strain Measurement Using Hyperelastic Warping, Application to Detecting Myocardial Dysfunction in Rat microPET Images." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 797-798. ASME. https://doi.org/10.1115/SBC2011-53654
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