Tendons and ligaments are soft connective tissues that play an important role in the musculoskeletal system. The tendon transmits the concentrated tensions generated by the muscle to the bone, and the ligaments stabilize and guide the movement between bones connected at the articulating joints. To perform these tasks, these soft connective tissues are uniquely built to bear load transmission, but are flexible enough to allow the changing direction in their paths of alignment. To accomplish these requirements, the tendons and ligaments have a hierarchy of highly aligned collagen structures consisting of fibrils, fascicles and fibers, along with the ground substance of proteoglycans and glycolipids to form the tendon and ligament tissues.

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