A torn anterior cruciate ligament (ACL) of the knee has poor healing potential, and thus, surgical reconstruction using soft tissue autografts is needed to restore knee stability. Unfortunately, these procedures have a high incidence of donor site morbidity and the progression to osteoarthritis in the long-term 1. In recent years, biological stimulation by means of growth factors and bioscaffolds has demonstrated successful early clinical results 2. Our research center has used extracellular matrix (ECM) bioscaffolds as a biological agent to improve ACL healing in a goat model 7, 8. Indeed, there was sufficient formation of neo-ACL tissue that led to up to a 30% reduction in the instability of the stifle joint by 12 weeks. Its biomechanical properties also increased by two-fold in comparison to those with suture repair alone 7, 8.
Skip Nav Destination
ASME 2011 Summer Bioengineering Conference
June 22–25, 2011
Farmington, Pennsylvania, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-5458-7
PROCEEDINGS PAPER
Extracellular Matrix Bioscaffolds to Enhance ACL Healing: Impact on the Contribution of the MCL to Joint Stability
Matthew B. Fisher,
Matthew B. Fisher
University of Pittsburgh, Pittsburgh, PA
Search for other works by this author on:
Ho-Joong Jung,
Ho-Joong Jung
University of Pittsburgh, Pittsburgh, PA
Chung-Ang University, Seoul, Korea
Search for other works by this author on:
Kwang E. Kim,
Kwang E. Kim
University of Pittsburgh, Pittsburgh, PA
Search for other works by this author on:
Patrick J. McMahon,
Patrick J. McMahon
University of Pittsburgh, Pittsburgh, PA
Search for other works by this author on:
Savio L-Y. Woo
Savio L-Y. Woo
University of Pittsburgh, Pittsburgh, PA
Search for other works by this author on:
Matthew B. Fisher
University of Pittsburgh, Pittsburgh, PA
Ho-Joong Jung
University of Pittsburgh, Pittsburgh, PA
Chung-Ang University, Seoul, Korea
Kwang E. Kim
University of Pittsburgh, Pittsburgh, PA
Patrick J. McMahon
University of Pittsburgh, Pittsburgh, PA
Savio L-Y. Woo
University of Pittsburgh, Pittsburgh, PA
Paper No:
SBC2011-53416, pp. 641-642; 2 pages
Published Online:
July 17, 2013
Citation
Fisher, MB, Jung, H, Kim, KE, McMahon, PJ, & Woo, SL. "Extracellular Matrix Bioscaffolds to Enhance ACL Healing: Impact on the Contribution of the MCL to Joint Stability." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 641-642. ASME. https://doi.org/10.1115/SBC2011-53416
Download citation file:
5
Views
Related Proceedings Papers
Related Articles
Does Graft Construct Lengthening at the Fixations Cause an Increase in Anterior Laxity Following Anterior Cruciate Ligament Reconstruction in vivo?
J Biomech Eng (August,2010)
Bioactive Magnetoelastic Materials as Coatings for Implantable Biomaterials
J. Med. Devices (June,2009)
Design of a Compliant Steerable Arthroscopic Punch
J. Med. Devices (June,2010)
Related Chapters
Introduction and Scope
High Frequency Piezo-Composite Micromachined Ultrasound Transducer Array Technology for Biomedical Imaging
Cruciate Ligament Injuries in Female Alpine Ski Racers
Skiing Trauma and Safety: Seventh International Symposium
An Extensometer for Soft Material Strain Measurement
Nontraditional Methods of Sensing Stress, Strain, and Damage in Materials and Structures