There are large numbers of physiological, material and geometrical parameters that influence the efficiency of clearance of mucus by cough in human airways. In this study the effect of ten independent variables on the displacement of simulated airway mucus in a rigid model trachea during cough is explored. This is the first attempt in combining these 10 parameters into a single non-dimensional group. Eight hundred (800) different combinations of these parameters are used to test its feasibility experimentally. All independent variables had variance inflation less than 10 indicating adequate independence among them. Although additional tests may be needed to confirm, the preliminary test results are promising.
- Bioengineering Division
A Study on the Parameters Influencing Clearance of Mucus During Cough in a Model Trachea
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Ragavan, AJ, Evrensel, CA, & Krumpe, P. "A Study on the Parameters Influencing Clearance of Mucus During Cough in a Model Trachea." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 545-546. ASME. https://doi.org/10.1115/SBC2011-53941
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