Stroke is a leading cause of death in the Western world (1). One reason for stroke is the rupture of aneurysms usually found in or near the Circle of Willis, an arterial network located at the base of the brain. It is estimated that 1–6% of the population harbor aneurysms during their lifetime (2), and that the average risk of rupture is 1–2% annually. The initiation, growth, and rupture of intracranial aneurysms are complex and multi-factorial processes. The precise mechanism however, is still not known. If the wall shear stress (WSS) exceeds a limit of 40 Pa, the endothelial cells are believed to be damaged, and an aneurysm might form (3) (4).
- Bioengineering Division
Direct Numerical Simulation of Transitional Flow in a Patient-Specific MCA Aneurysm
- Views Icon Views
- Share Icon Share
- Search Site
Valen-Sendstad, K, Mardal, K, Mortensen, M, Reif, BAP, & Langtangen, HP. "Direct Numerical Simulation of Transitional Flow in a Patient-Specific MCA Aneurysm." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 259-260. ASME. https://doi.org/10.1115/SBC2011-53306
Download citation file: