Throughout the cardiac cycle the Mitral Valve (MV) experiences complex mechanical and hemodynamic loading [1]. Dysfunction of the MV may have devastating consequences and has been associated with high morbidity and mortality. Surgical repair techniques are available to treat malfunctioning MVs [2]. However, it is likely that interventions such as surgical repair may cause alterations in the loading conditions and associated deformations of the MV. In consequence such alterations could result in detrimental remodeling and disturb normal valve function. It is therefore essential to characterize the MV under in-vivo conditions as accurately as possible and thereby establish a baseline of the normal valve. Even though excellent research has been conducted in-vivo [3], in-vitro [4], as well as in-silico [5], the Anterior Mitral Valve Leaflet (AMVL) has never been characterized from a mechanical perspective across its entire surface. The goal of this study is, hence, to provide a more complete picture of the deformations across the entire AMVL in the beating heart.
Skip Nav Destination
ASME 2011 Summer Bioengineering Conference
June 22–25, 2011
Farmington, Pennsylvania, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-5458-7
PROCEEDINGS PAPER
In-Vivo Dynamic Strains of the Ovine Anterior Mitral Valve Leaflet Available to Purchase
Manuel Rausch,
Manuel Rausch
Stanford University, Stanford, CA
Search for other works by this author on:
Wolfgang Bothe,
Wolfgang Bothe
Stanford School of Medicine, Stanford, CA
Search for other works by this author on:
John-Peder Escobar-Kvitting,
John-Peder Escobar-Kvitting
Stanford School of Medicine, Stanford, CA
Search for other works by this author on:
Serdar Goktepe,
Serdar Goktepe
Stanford University, Stanford, CA
Search for other works by this author on:
Craig Miller,
Craig Miller
Stanford School of Medicine, Stanford, CA
Search for other works by this author on:
Ellen Kuhl
Ellen Kuhl
Stanford University, Stanford, CA
Stanford School of Medicine, Stanford, CA
Search for other works by this author on:
Manuel Rausch
Stanford University, Stanford, CA
Wolfgang Bothe
Stanford School of Medicine, Stanford, CA
John-Peder Escobar-Kvitting
Stanford School of Medicine, Stanford, CA
Serdar Goktepe
Stanford University, Stanford, CA
Craig Miller
Stanford School of Medicine, Stanford, CA
Ellen Kuhl
Stanford University, Stanford, CA
Stanford School of Medicine, Stanford, CA
Paper No:
SBC2011-53195, pp. 249-250; 2 pages
Published Online:
July 17, 2013
Citation
Rausch, M, Bothe, W, Escobar-Kvitting, J, Goktepe, S, Miller, C, & Kuhl, E. "In-Vivo Dynamic Strains of the Ovine Anterior Mitral Valve Leaflet." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 249-250. ASME. https://doi.org/10.1115/SBC2011-53195
Download citation file:
7
Views
Related Proceedings Papers
Related Articles
Visualization and Hemo-Dynamic Evaluation of Edge-to-Edge Mitral Valve Repair Within Reanimated Swine Hearts
J. Med. Devices (June,2009)
A Design Framework of Unloaded Leaflet Shape for the Ovine Pulmonary Valve Single Leaflet Replacement Surgery
J. Med. Devices (June,2011)
Related Chapters
mDFA Human Empirical Results
Modified Detrended Fluctuation Analysis (mDFA)
Chapter 4 | Panel Maintenance
Guidelines for the Selection and Training of Sensory Panel Members
Development and Structure of the German Common Cause Failure Data Pool (PSAM-0020)
Proceedings of the Eighth International Conference on Probabilistic Safety Assessment & Management (PSAM)