The primary goal in treating heart attack is to restore blood flow to blocked areas of the heart. However, even after blood flow is restored, injury can occur as a result of a complex cascade of mechanisms following the reintroduction of flow, aptly referred to as reperfusion injury. Studies show that reperfusion injury is accountable for up to 50% of cell death following an ischemic period [1]. Adjunctive therapies are needed to reduce reperfusion injury.

Volume Subject Area:
Cardiovascular Design and Devices II
Topics:
Biological tissues, Blood flow, Cascades (Fluid dynamics), Cooling, Flow (Dynamics), Patient treatment, Salvage (Wastes), Wounds
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