The primary goal in treating heart attack is to restore blood flow to blocked areas of the heart. However, even after blood flow is restored, injury can occur as a result of a complex cascade of mechanisms following the reintroduction of flow, aptly referred to as reperfusion injury. Studies show that reperfusion injury is accountable for up to 50% of cell death following an ischemic period . Adjunctive therapies are needed to reduce reperfusion injury.
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Localized Cooling Device for Myocardial Tissue Salvage
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Akers, JE, Merrill, DR, Nilsen, TJ, Koomalsingh, KJ, Minakawa, M, Shuto, T, Gorman, JH, III, Gorman, RC, Gillespie, MJ, & Merrill, TL. "Localized Cooling Device for Myocardial Tissue Salvage." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 171-172. ASME. https://doi.org/10.1115/SBC2011-53155
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