The whole cadaveric rat heart can be perfused with a detergent to completely decellurize the tissue . What remains is a three-dimensional scaffold that can be repopulated with neonatal cardiac cells or rat aortic endothelial cells. However, in the development of a biological substitute to replace a tissue or organ, a critical question is how to evaluate the proposed substitute.
Volume Subject Area:Cardiac Mechanics
Topics:Anisotropy, Biological tissues, Detergents, Endothelial cells
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