Development of a Computational Model of Lymphangions in Series: A Parameter Sensitivity Analysis

The lymphatic system plays a vital role in the body to maintain normal health. The lymphatics are responsible for fluid and protein balance, as they transport approximately 3.6 liters/day of fluid from the interstitial spaces to the venous circulation. Throughout this transfer process, both positive and negative events can occur. Undesirable pathogens are typically destroyed in lymph nodes, but since it serves as the primary transport mechanism for the immune system, it is also involved in the spread of pathogens such as cancer cells.