Our laboratory developed an electrochemical method which transforms collagen solutions to solid state material by densification and unidirectional alignment of molecules  based on the principles of isoelectric focusing (IEF). Randomly oriented molecules at the onset migrate to the isoelectic plane when current is applied to the solution. However, the driving forces behind the focusing phenomena are not fully understood.
- Bioengineering Division
Modeling of Isoelectric Focusing of Type-I Collagen Molecules Under Uniform Electric Field
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Uquillas, JA, & Akkus, O. "Modeling of Isoelectric Focusing of Type-I Collagen Molecules Under Uniform Electric Field." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 1247-1248. ASME. https://doi.org/10.1115/SBC2011-53185
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