Cells of the artery can respond to mechanical cues in a variety of ways including proliferation, migration, protein secretion, phenotype modulation, and orientation [4, 6]. Many of these responses are related to the progression of disease such as atherosclerosis, emphasizing a need to understand how mechanical signals are translated into biological behaviors. Much work has been done to isolate the effects of particular mechanical inputs on particular cellular responses with rather simple mechanical environments, e.g. uniaxial or uniform equibiaxial stretching. Such experiments have greatly improved our knowledge of mechanobiology, yet many questions regarding these cell responses remain unaddressed; in particular, the effect of non-uniform stretch environments.
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ASME 2011 Summer Bioengineering Conference
June 22–25, 2011
Farmington, Pennsylvania, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-5458-7
PROCEEDINGS PAPER
Smooth Muscle Cell Orientation on Non-Uniform Stretch Environments Available to Purchase
William J. Richardson,
William J. Richardson
Texas A&M University, College Station, TX
Search for other works by this author on:
James E. Moore, Jr.
James E. Moore, Jr.
Texas A&M University, College Station, TX
Search for other works by this author on:
William J. Richardson
Texas A&M University, College Station, TX
James E. Moore, Jr.
Texas A&M University, College Station, TX
Paper No:
SBC2011-53713, pp. 1243-1244; 2 pages
Published Online:
July 17, 2013
Citation
Richardson, WJ, & Moore, JE, Jr. "Smooth Muscle Cell Orientation on Non-Uniform Stretch Environments." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 1243-1244. ASME. https://doi.org/10.1115/SBC2011-53713
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