Bio-prosthetic heart valves (BHVs) with leaflets made of glutaraldehyde-treated bovine pericardium (GLBP), have been used extensively to replace diseased heart valves. BHVs display superior hemodynamics to mechanical valves and eliminate the need for anticoagulant therapy; however, they exhibit poor durability resulting from in vivo degradation and fatigue damage of the leaflets.
- Bioengineering Division
Modeling of Tissue Fatigue Damage in Bio-Prosthetic Heart Valve
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Martin, C, & Sun, W. "Modeling of Tissue Fatigue Damage in Bio-Prosthetic Heart Valve." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 1217-1218. ASME. https://doi.org/10.1115/SBC2011-53888
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