A Novel Approach to Quantify Alterations in Ventricular Principal Strain Vectors Secondary to Ischemic Injury

Accurate assessment of regional and global left ventricular (LV) function is critical for understanding ischemic heart disease. The orientation and the magnitude of the myocardial principal strains have been shown to be sensitive to ischemic development [1]. Combing MR tagging, cardiac mechanics, and computer visualization, this study presents a novel method to fully characterize the alterations in the magnitude and orientations of principal strains in the LV post-infarct.