Moduli and Stress Patterns Determined From Heterogeneous MRI-Based Strains

Characterization of stress and strain patterns in load-bearing tissue such as articular cartilage is key to developing successful treatment strategies for osteoarthritis, a degenerative disease affecting 27 million people in the United States alone [1]. Moreover, knowledge of the stress and mechanical properties of cartilage provides a more comprehensive characterization of tissue integrity during tissue degeneration or repair.